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Aubrey Milunsky Genetic Disorders and the Fetus. Diagnosis, Prevention, and Treatment

Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, Seventh Edition is the eagerly awaited new edition of the discipline-leading text that has been at the forefront of diagnosis, prevention, and treatment of fetal genetic disorders for over 36 years. The seventh edition continues the long-established tradition of excellence that has become synonymous with this text. The book builds on the foundations of preconception and prenatal genetic counseling and the original pillars of prenatal diagnosis while also providing authoritative coverage of exciting developments in non-invasive genetic testing and rapidly developing molecular techniques, including microarray analysis and next generation sequencing, that are revolutionizing the field. Chapters are once again authored by internationally recognized authorities in the field of prenatal diagnosis. The editors have added three entirely new chapters to this edition to complement the complete revision of existing content. The three new chapters focus on non-invasive prenatal screening, placental genetics, and the psychology of prenatal and perinatal grief. The broad-ranging coverage and international scope will ensure that the new edition maintains its role as the major repository for information on all aspects of prenatal diagnosis. The editors have brought together an invaluable collection of evidence-based facts bolstered by knowledge and decades of experience in the field. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, 7th Edition is a timely update to this world-leading text.

18741.83 рублей

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Richard Crisp J. The Psychology of Social and Cultural Diversity

Promoting a scholarly understanding of the psychology of social and cultural diversity in the early stages of 21st century, this volume encourages an in-depth appreciation of the value in diversity while directly addressing social intervention and policy implications. Offers, for the very first time, an integrated approach to the issues raised by increasingly complex representations of social identity Explores the psychological implications and applications of new forms of social and cultural diversity Includes research from a diverse range of scholars that covers a broad spectrum of sub-disciplines Discusses how the applications of multiculturalism and diversity research can encourage more positive intergroup relations Develops an in depth understanding and appreciation of the value of social and cultural diversity

9805.06 рублей

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Thomas Schafer Automatische genetische Analytik

The relevance of genetic analysis and the need of its automation have rapidly increased during the last years not only in molecular biology and medicine but particularly in fields outside these 'classical' areas of application. In forensic medicine and criminology, e.g., DNA analysis has become a routine method – and a similar development is just ongoing in fields like anthropology, paleontology, plant and animal breeding, and food production. This book provides a comprehensive and practical overview of the methods – from biological material and analytical processes to the analysis and processing of data – and provides insights into various important applications. Clearly written and nicely illustrated with color figures the book will serve as a useful source of information for a broad spectrum of (potential) users of DNA analysis.

7123.25 рублей

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Martin Kent Vegetation Description and Data Analysis. A Practical Approach

Vegetation Description and Data Analysis: A Practical Approach, Second Edition is a fully revised and up-dated edition of this key text. The book takes account of recent advances in the field whilst retaining the original reader-friendly approach to the coverage of vegetation description and multivariate analysis in the context of vegetation data and plant ecology. Since the publication of the hugely popular first edition there have been significant developments in computer hardware and software, new key journals have been established in the field and scope and application of vegetation description and analysis has become a truly global field. This new edition includes full coverage of new developments and technologies. This contemporary and comprehensive edition of this well-known and respected textbook will prove invaluable to undergraduate and graduate students in biological sciences, environmental science, geography, botany, agriculture, forestry and biological conservation. Fully international approach Includes illustrative case studies throughout Now with new material on: the nature of plant communities; transitional areas between plant communities; induction and deduction of plant ecology; diversity indices and dominance diversity curves; multivariate analysis in ecology. Accessible, reader-friendly style Now with new and improved illustrations

2139.84 рублей

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Bryan Shorrocks The Giraffe. Biology, Ecology, Evolution and Behaviour

Provides a comprehensive overview of one of nature's most engaging mammals Covers fossil history, taxonomy, genetics, physiology, biomechanics, behavior, ecology, and conservation Includes genetic analysis of five of the six subspecies of modern giraffes Includes giraffe network studies from Laikipia Kenya, Etosha National Park, Namibia andSamburu National Reserve, Kenya

5998.52 рублей

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Patricia Harris Sowell None of Us is As Good As All of Us. How McDonald's Prospers by Embracing Inclusion and Diversity

An inside account of how McDonald's turns diversity into success Everyone knows McDonald's, one of the most recognizable brand names in the world. But few know the extent to which McDonald's continued and ongoing success is due to the company's internal philosophy of inclusion and diversity. One of the biggest employers in the world, McDonald's staff is one of the world's most racially, culturally, and religiously diverse. In None of Us Is As Good As All of Us, McDonald's Global Chief Diversity Officer, Patricia Sowell Harris, offers the first inside look at the company's philosophy of inclusion and diversity through interviews with more than 60 key employees and leaders. These accounts, of franchisees, suppliers, and employees, reveal how McDonald's embraces all races, creeds, and cultures to create unity and business achievement. • Written by Patricia Sowell Harris, McDonald's global chief diversity officer • Serves as a template for any business that wants to embrace wider diversity and use it to prosper • With a Foreword by Jim Skinner, McDonald's CEO since 2004 • A first look at the inner workings of McDonald's impressive diversity and inclusion philosophy For any business leader who wants to embrace diversity and encourage team unity, None of Us Is As Good As All of Us offers inspiration and guidance.

1913.99 рублей

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Bleuenn Guilloux Marine Genetic Resources 1

Advances in research and development reveal the immense diversity and potential of marine genetic resources. Under international law, no specific regime applies to these complex and paradoxical objects of use. The Law of the Sea Convention sets a framework that is partly inadequate for this new category of resources. The Biodiversity Convention and the Nagoya Protocol only address the genetic resources of national areas. Patents allow their holder to exercise a monopoly on exploiting biotechnological creations to extensive claims, questioning the common nature of biodiversity and related knowledge. They hinder research and the objectives of biodiversity law. The legal and practical rules of physical and functional access vary in geometry. They focus on the valorization of research results, crystallizing conflicts of interest between suppliers and users. Sustainable research and development is essential to the knowledge and protection of marine biodiversity. The qualification of marine genetic resources in common, standard contractual tools, distributed research and development infrastructures, negotiation of an agreement on sustainable use and conservation of biodiversity beyond the limits of national jurisdiction, would To remove these inconsistencies.

9259.7 рублей

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Yonghong Xu Jade Refining the Focus on Faculty Diversity in Postsecondary Institutions. New Directions for Institutional Research, Number 155

Faculty diversity is gaining unprecedented emphasis in the mission of colleges and universities, and institutional researchers are being pushed for relevant data. This volume examines faculty diversity from a variety of perspectives. Together, they constitute a comprehensive outlook on the subject, highlighting factors including racial background, gender, citizenship, employment status, and academic discipline, and examining how growing diversity has affected the work experience and productivity of faculty and the learning outcomes of students. Special attention is given to international and nontenure-track faculty members, two groups that have experienced rapid growth in recent years. The authors: Present empirical evidence to support the increasing importance of faculty diversity in institutional research Show the need for actively tracking the changes in diversity over time Highlight the critical role of research methodology in all such work. This is the 155th volume of this Jossey-Bass quarterly report series. Always timely and comprehensive, New Directions for Institutional Research provides planners and administrators in all types of academic institutions with guidelines in such areas as resource coordination, information analysis, program evaluation, and institutional management.

2220.23 рублей

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Linacre Adrian Wildlife DNA Analysis. Applications in Forensic Science

DNA typing of non-human DNA is a fast developing area of research and professional practice. The application of DNA typing in wildlife forensic science is one of these prime uses of DNA typing and is gaining increasing profile. The use of DNA profiling in wildlife forensic science falls into two broad areas: species testing and genetic linkage. Species testing answers the question ‘what species is this?’ and genetic linkage answers the question ‘did these two samples come from the same organism or population?’ Wildlife DNA Analysis: Applications in Forensic Science provides an accessible introduction to both of these key areas. Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements. •An accessible introduction to this fast developing area of research within forensic science •Case studies throughout to link theory and practice and to highlight the use of DNA testing in species testing. •Covers both crimes against wildlife and offences where wildlife can provide vital evidence •Assumes only a basic background knowledge of DNA •Includes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons

12257.29 рублей

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Mark Stoneking An Introduction to Molecular Anthropology

Molecular anthropology uses molecular genetic methods to address questions and issues of anthropological interest. More specifically, molecular anthropology is concerned with genetic evidence concerning human origins, migrations, and population relationships, including related topics such as the role of recent natural selection in human population differentiation, or the impact of particular social systems on patterns of human genetic variation. Organized into three major sections, An Introduction to Molecular Anthropology first covers the basics of genetics – what genes are, what they do, and how they do it – as well as how genes behave in populations and how evolution influences them. The following section provides an overview of the different kinds of genetic variation in humans, and how this variation is analyzed and used to make evolutionary inferences. The third section concludes with a presentation of the current state of genetic evidence for human origins, the spread of humans around the world, the role of selection and adaptation in human evolution, and the impact of culture on human genetic variation. A final, concluding chapter discusses various aspects of molecular anthropology in the genomics era, including personal ancestry testing and personal genomics. An Introduction to Molecular Anthropology is an invaluable resource for students studying human evolution, biological anthropology, or molecular anthropology, as well as a reference for anthropologists and anyone else interested in the genetic history of humans.

9744.05 рублей

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Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

11997.76 рублей

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Lue Neal Telomerases. Chemistry, Biology and Clinical Applications

This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.

10498.58 рублей

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Salah Khalfallah Structural Analysis 1. Statically Determinate Structures

Using a general approach, this book supports the student to enable mastery of the methods of analysis of isostatic and hyperstatic structures. To show the performance of the methods of analysis of the hyperstatic structures, selected beams, gantries and reticular structures are selected and subjected to a comparative study by the different methods of analysis of the hyperstatic structures.

10536.9 рублей

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Mackenzie Lynette Occupation Analysis in Practice

Occupation Analysis in Practice is the essential book for all future and current occupational therapists. It offers a practical approach to the analysis of occupations in real world practice. The book frames occupation as the key component for analysis and builds upon previous work limited to analysis at the activity level. It examines the interests, goals, abilities and contexts of individuals, groups, institutions and communities, along with the demands of the occupation. It presents examples of occupation analysis in different practice context including working with children, health promotion, indigenous health, medico-legal practice; mental health and occupational rehabilitation. The book has four sections. Section 1 introduces theoretical perspectives of the concept of occupation analysis and how such analysis relates to particular models of Occupational Therapy practice and the generic World Health Organisation International Classification of Functioning, Disability and Health. Section 2 discusses analysis of particular components of occupation that support practice. These include culture, spirituality, home and community environments as well as self-care and leisure. Section 3 applies analysis of occupations to particular specialties encountered in practice. Section 4 considers the application of Occupation Analysis within professional reasoning and goal setting. FEATURES International team of contributors Examples of occupation analysis proforma Application to a wide range of practice areas. Glossary of key terms Incudes the International Classification of Functioning, Disability and Health.

4444.02 рублей

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DNA typing of non-human DNA is a fast developing area of research and professional practice. The application of DNA typing in wildlife forensic science is one of these prime uses of DNA typing and is gaining increasing profile. The use of DNA profiling in wildlife forensic science falls into two broad areas: species testing and genetic linkage. Species testing answers the question ‘what species is this?’ and genetic linkage answers the question ‘did these two samples come from the same organism or population?’ Wildlife DNA Analysis: Applications in Forensic Science provides an accessible introduction to both of these key areas. Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements. •An accessible introduction to this fast developing area of research within forensic science •Case studies throughout to link theory and practice and to highlight the use of DNA testing in species testing. •Covers both crimes against wildlife and offences where wildlife can provide vital evidence •Assumes only a basic background knowledge of DNA •Includes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons

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