sweta tripathi ravi gor and himanshu pandya microarray analysis on alzheimer s disease

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Dhammika Amaratunga Exploration and Analysis of DNA Microarray and Other High-Dimensional Data

Praise for the First Edition “…extremely well written…a comprehensive and up-to-date overview of this important field.” – Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysis New topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methods Updated exercises to deepen knowledge of the presented material and provide readers with resources for further study The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics.

9278.52 рублей

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Lindsey Snyder B.C. Canine and Feline Anesthesia and Co-Existing Disease

Canine and Feline Anesthesia and Co-Existing Disease is the first book to draw together clinically relevant information on the anesthetic management of dogs and cats with existing disease conditions. Providing a detailed reference on avoiding and managing complications resulting from concurrent disease, the book offers a ready reference for handling anesthesia in patients with common presenting diseases. Organized by body system, Canine and Feline Anesthesia and Co-Existing Disease is designed to allow the reader to quickly find and apply advice for anesthetizing patients with specific conditions. Each chapter presents in-depth, practical information on the special considerations before, during, and after sedation and anesthesia of a patient with a given disease. Canine and Feline Anesthesia and Co-Existing Disease is a useful reference for general practitioners, veterinary students, specialists in a variety of areas, and veterinary anesthesiologists alike.

7465.04 рублей

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Andreas Scherer Batch Effects and Noise in Microarray Experiments. Sources and Solutions

Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.

9413.64 рублей

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Robert Dingwall Pandemics and Emerging Infectious Diseases. The Sociological Agenda

Infectious disease pandemics are a rising threat in our globalizing world. This agenda-setting collection provides international analysis of the pressing sociological concerns they confront us with, from cross-border coordination of public health governance to geopolitical issues of development and social equity. Focuses on vital sociological issues raised by resurgent disease pandemics Detailed analysis of case studies as well as broader, systemic factors Contributions from North America, Europe and Asia provide international perspective Bold, agenda-setting treatment of a high-profile topic

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B. A. Kazakovtsev Mental Disorders in Epilepsy

The monograph shows the opportunity to study the pathogenesis of mental disorders in epilepsy based on the characteristics of its fl ow using clinical methods, structural dynamic, epidemiological and statistical analysis. Structural and dynamic analysis of the major clinical manifestations of the disease (features of personality changes, paroxysmal disorders, psychotic symptoms, dementia) held in accordance with the main patterns of development of the disease, its types and stages. On the basis of the multi-axial classifi cation of epilepsy was developed a model that allows in a retrospective analysis of an-amnestic data and clinical assessment to establish clinical and social criteria for prognosis prediction.

400 рублей

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Kazakovtsev B. A. Mental Disorders in Epilepsy

The monograph shows the opportunity to study the pathogenesis of mental disorders in epilepsy based on the characteristics of its flow using clinical methods, structural dynamic, epidemiological and statistical analysis. Structural and dynamic analysis of the major clinical manifestations of the disease (features of personality changes, paroxysmal disorders, psychotic symptoms, dementia) held in accordance with the main patterns of development of the disease, its types and stages. On the basis of the multi-axial classification of epilepsy was developed a model that allows in a retrospective analysis of anamnestic data and clinical assessment to establish clinical and social criteria for prognosis prediction

1199 рублей

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Ruth Lynfield Infectious Disease Surveillance

This fully updated edition of Infectious Disease Surveillance is for frontline public health practitioners, epidemiologists, and clinical microbiologists who are engaged in communicable disease control. It is also a foundational text for trainees in public health, applied epidemiology, postgraduate medicine and nursing programs. The second edition portrays both the conceptual framework and practical aspects of infectious disease surveillance. It is a comprehensive resource designed to improve the tracking of infectious diseases and to serve as a starting point in the development of new surveillance systems. Infectious Disease Surveillance includes over 45 chapters from over 100 contributors, and topics organized into six sections based on major themes. Section One highlights the critical role surveillance plays in public health and it provides an overview of the current International Health Regulations (2005) in addition to successes and challenges in infectious disease eradication. Section Two describes surveillance systems based on logical program areas such as foodborne illnesses, vector-borne diseases, sexually transmitted diseases, viral hepatitis healthcare and transplantation associated infections. Attention is devoted to programs for monitoring unexplained deaths, agents of bioterrorism, mass gatherings, and disease associated with international travel. Sections Three and Four explore the uses of the Internet and wireless technologies to advance infectious disease surveillance in various settings with emphasis on best practices based on deployed systems. They also address molecular laboratory methods, and statistical and geospatial analysis, and evaluation of systems for early epidemic detection. Sections Five and Six discuss legal and ethical considerations, communication strategies and applied epidemiology-training programs. The rest of the chapters offer public-private partnerships, as well lessons from the 2009-2010 H1N1 influenza pandemic and future directions for infectious disease surveillance.

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Bendat Julius S. Random Data. Analysis and Measurement Procedures

A timely update of the classic book on the theory and application of random data analysis First published in 1971, Random Data served as an authoritative book on the analysis of experimental physical data for engineering and scientific applications. This Fourth Edition features coverage of new developments in random data management and analysis procedures that are applicable to a broad range of applied fields, from the aerospace and automotive industries to oceanographic and biomedical research. This new edition continues to maintain a balance of classic theory and novel techniques. The authors expand on the treatment of random data analysis theory, including derivations of key relationships in probability and random process theory. The book remains unique in its practical treatment of nonstationary data analysis and nonlinear system analysis, presenting the latest techniques on modern data acquisition, storage, conversion, and qualification of random data prior to its digital analysis. The Fourth Edition also includes: A new chapter on frequency domain techniques to model and identify nonlinear systems from measured input/output random data New material on the analysis of multiple-input/single-output linear models The latest recommended methods for data acquisition and processing of random data Important mathematical formulas to design experiments and evaluate results of random data analysis and measurement procedures Answers to the problem in each chapter Comprehensive and self-contained, Random Data, Fourth Edition is an indispensible book for courses on random data analysis theory and applications at the upper-undergraduate and graduate level. It is also an insightful reference for engineers and scientists who use statistical methods to investigate and solve problems with dynamic data.

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Allen John Pathological Lives. Disease, Space and Biopolitics

Pandemics, epidemics and food borne diseases are a major global challenge. Focusing on the food and farming sector, and mobilising social theory as well as empirical enquiry, Pathological Lives investigates current approaches to biosecurity and ask how pathological lives can be successfully ‘regulated’ without making life more dangerous as a result. Uses empirical and social theoretical resources developed in the course of a 40-month research project entitled ‘Biosecurity borderlands’ Focuses on the food and farming sector, where the generation and subsequent transmission of disease has the ability to reach pandemic proportions Demonstrates the importance of a geographical and spatial analysis, drawing together social, material and biological approaches, as well as national and international examples The book makes three main conceptual contributions, reconceptualising disease as situated matters, the spatial or topological analysis of situations and a reformulation of biopolitics Uniquely brings together conceptual development with empirically and politically informed work on infectious and zoonotic disease, to produce a timely and important contribution to both social science and to policy debate

6882.55 рублей

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Jianhong Wu Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases

Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.

10147.77 рублей

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Eskild Petersen Infectious Diseases. A Geographic Guide

The second edition of this concise and practical guide describes infections in geographical areas and provides information on disease risk, concomitant infections (such as co-prevalence of HIV and tuberculosis) and emerging bacterial, viral and parasitic infections in a given geographical area of the world. Geographic approach means that it?s the only book to guide the health care worker towards a diagnosis based on the location of symptoms and travel history by encouraging the question ?where have you been?? New content covering MERS, Ebola, Zika, and infections transmitted during air and maritime travel Covers the major infectious disease outbreaks framed in their geographic setting such as H7N9 ?bird flu? influenza, H1N1, Ebola, and Zika Outstanding international editor team with vast experience on various international infectious disease and as journal editors and key leaders in infection surveillance

7969.13 рублей

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Paul Moayyedi GI Epidemiology. Diseases and Clinical Methodology

Identifying how, why and in whom gastrointestinal disease occurs, and what can be done to prevent it, is of key importance for the modern-day gastroenterologist and researcher. Brought to you by the world’s leading gastroenterologists, the second edition of GI Epidemiology: Diseases and Clinical Methodology is the only book that combines detailed analysis of the epidemiology of GI disease with a study of the methodology of clinical research. With a much greater clinical focus on the diagnostic and management approach for each disease than before, all existing chapters are fully updated with the very latest in statistical and clinical data. In addition, the revised edition contains several significant improvements, notably: • Five extra disease epidemiology chapters: Upper GI Bleeding; Hepatitis B and C; Common Tropical GI Diseases; Nutritional Epidemiology and GI Cancers; and Obesity among Adults • More illustrations, including maps of each disease • A more international focus with the inclusion of two experienced European editors • MCQs, summary checklists and key points throughout • Ten extra online-only chapters on methodological issues related to GI epidemiology such as Patient reported GI Epidemiology: Diseases and Clinical Methodology, 2nd Edition is the perfect reference tool for gastroenterologists involved in both patient management and clinical research, and also for epidemiologists involved specifically in GI disease data and more general epidemiological studies. Titles of Related Interest Yamada’s Handbook of Gastroenterology, 3rd Edition Yamada; ISBN 9780470656204 Essentials of Gastroenterology Friedman; ISBN 9780470656259

12319.55 рублей

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Susan Zneimer Mahler Cytogenetic Abnormalities. Chromosomal, FISH, and Microarray-Based Clinical Reporting and Interpretation of Result

This guide discusses chromosomal abnormalities and how best to report and communicate lab findings in research and clinical settings. Providing a standard approach to writing cytogenetic laboratory reports, the guide further covers useful guidance on implementing International System for Human Cytogenetic Nomenclature in reports. Part one of the guide explores chromosomal, FISH, and microarray analysis in constitutional cytogenetic analyses, while part two looks at acquired abnormalities in cancers. Both sections provide illustrative examples of chromosomal abnormalities and how to communicate these findings in standardized laboratory reports.

10335.71 рублей

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Melissa Kennedy Veterinary Microbiology

Veterinary Microbiology, Third Edition is a comprehensive reference on the bacterial, fungal, and viral pathogenic agents that cause animal disease. Now in full color with improved images throughout, the new edition has been thoroughly updated to reflect information from current research and diagnostic and clinical publications. Key changes include a review of microbial cell structure and function and increased emphasis on the key points of pathogenesis and host responses to infection. Organized into four sections, the Third Edition begins with an updated and expanded introductory section on infectious disease pathogenesis, diagnosis and clinical management. The second section covers bacterial and fungal pathogens, and the third section describes viral diseases and viruses. The final section presents a systematic approach of describing infection and disease of animals. Equally useful for beginning veterinary students and seasoned practitioners, Veterinary Microbiology offers a thorough introduction and reference text for veterinary infectious disease.

7683.04 рублей

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Mike Lee S. Protein Analysis using Mass Spectrometry. Accelerating Protein Biotherapeutics from Lab to Patient

Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs , instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives Brings together the most current advances in the mass spectrometry technology and related method in protein analysis

12684.72 рублей

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James Fingeroth Advances in Intervertebral Disc Disease in Dogs and Cats

Advances in Intervertebral Disc Disease in Dogs and Cats defines our present knowledge of this common clinical problem, compiling information related to the canine and feline intervertebral disc into a single resource. As a comprehensive, focused work, the book is an authoritative reference for understanding and treating disc disease, providing a sound scientific and clinical basis for decision making. Offering an objective synthesis of the current literature, the book supplies guidance on the approach to a potential disc rupture, surgical and medical strategies, and management of the patient. Offering a complete understanding of intervertebral disc disease, the book describes and discusses the controversies and issues surrounding this topic, acknowledging the gaps in our knowledge. Advances in Intervertebral Disc Disease in Dogs and Cats presents up-to-date, reliable information on this common condition for veterinary surgeons, neurologists, and general practitioners.

9350.04 рублей

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Ralph Rapley Molecular Analysis and Genome Discovery

Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical information on current techniques currently being researched and developed. Each chapter offers an up-to-date analysis of the subject encompassing the very latest technology platforms and is an essential reference for researchers in the field looking for an up-to-date overview of the subject. The book will also be an indispensable resource for those working in the biotechnology and pharmaceutical industries. New for this edition: chapters on Genotyping through Mutation Detection; Differential Gene Expression; Haplotyping and Molecular Profiling.

11594.02 рублей

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Sara Stanner Cardiovascular Disease. Diet, Nutrition and Emerging Risk Factors

A comprehensive, accessible summary of the latest research in heart disease risk factors Cardiovascular Disease (CVD) is a major cause of early death and disability across the world. The major markers of risk—including high blood cholesterol, smoking, and obesity—are well known, but studies show that such markers do not account for all cardiovascular risk. Written by a team of renowned experts in the field, this comprehensive and accessible book examines the evidence for emerging and novel risk factors, and their relationship with diet and nutrition. Fully updated throughout, Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition covers everything from the epidemiology of cardiovascular disease, to genetic factors, to inflammation and much more – offering invaluable advice on reducing risk factors and preventing CVD. This new edition: Authoritatively reports on the link between emerging aspects of diet, lifestyle and cardiovascular disease risk Focuses on novel risk factors of CVD, including the human gut microbiome and fetal and childhood origins, and how it can be prevented Features recommendations for interventions and future research Includes references, commonly asked questions that summarise the take-home messages, and an online glossary Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition is an important book for researchers and postgraduate students in nutrition, dietetics, food science, and medicine, as well as for cardiologists and cardiovascular specialists.

6714.06 рублей

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Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.

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