shah hussain sea buckthorn a source of antioxidants against oxidative stress

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Frederick Villamena A. Molecular Basis of Oxidative Stress. Chemistry, Mechanisms, and Disease Pathogenesis

Sets the stage for the development of better diagnostic techniques and therapeutics Featuring contributions from an international team of leading clinicians and biomedical researchers, Molecular Basis of Oxidative Stress reviews the molecular and chemical bases of oxidative stress, describing how oxidative stress can lead to the development of cancer and cardiovascular and neurodegenerative diseases. Moreover, it explains the potential role of free radicals in both the diagnosis and the development of therapeutics to treat disease. Molecular Basis of Oxidative Stress is logically organized, beginning with a comprehensive discussion of the fundamental chemistry of reactive species. Next, the book: Presents new mechanistic insights into how oxidative damage of biomolecules occurs Examines how these oxidative events effect cellular metabolism Investigates the role of oxidative stress in the pathogenesis of cancer, neurodegenerative disease, cardiovascular disease, and cystic fibrosis Explores opportunities to improve the diagnosis of disease and the design of new therapeutic agents Readers will find much novel information, including new radical chemistries and the latest discoveries of how free radicals react with biomolecules. The contributors also present recent findings that help us better understand the initiation of oxidative stress and the mechanisms leading to the pathogenesis of various diseases. Throughout the book, the use of molecular structures helps readers better understand redox chemistry. In addition, plenty of detailed figures illustrate the mechanisms of oxidative stress and disease pathogenesis. Examining everything from the basic chemistry of oxidative stress to the pathogenesis of disease, Molecular Basis of Oxidative Stress will help readers continue to explore the nature of oxidative stress and then use that knowledge to develop new approaches to prevent, detect, and treat a broad range of disease conditions.

11598.14 рублей

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Doris Abele Oxidative Stress in Aquatic Ecosystems

Reactive oxygen species (ROS) are increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific habitat conditions and how they affect susceptibility to ROS damage. A comprehensive and detailed methods section is included which supplies complete protocols for analyzing ROS production, oxidative damage, and antioxidant systems. Methods are also evaluated with respect to applicability and constraints for different types of research. The authors are all internationally recognized experts in particular fields of oxidative stress research. This comprehensive reference volume is essential for students, researchers, and technicians in the field of ROS research, and also contains information useful for veterinarians, environmental health professionals, and decision makers.

13481.77 рублей

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Yunus Oghuz Nader Shah. Historical novel

“Nader shah” is a voluminous novel. Nader shah was a historical person. He created a great Empire that encompassed Iran, southern Caucasus, northern India, and parts of Central Asia. He won battles against the Afghans, Ottomans, and Mughals. Nader Shah’s victories made him briefly the Middle East’s most powerful sovereign, but his empire quickly disintegrated after he was assassinated in 1747. Nader Shah was the last great Asia warlord.

200 рублей

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Donald Armstrong Oxidative Stress and Antioxidant Protection. The Science of Free Radical Biology and Disease

Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and< Disease provides an overview of the basic principles of free radical formation. The text delves into free radical formation in molecular biology and its effect on subcellular damage, as well as the role of antioxidant reserves as a protective mechanism. Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

10869.18 рублей

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Joaquim Ros Protein Carbonylation. Principles, Analysis, and Biological Implications

Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtman’s lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed. Oxidative stress occurs in all living organisms and affects proteins and other macromolecules: Protein carbonylation is a measure of oxidative stress in biological systems Mass spectrometry, fluorescent labelling, antibody based detection, biotinylated protein selection and other methods for detecting protein carbonyls and modification sites in proteins are described Aging, neurodegenerative diseases, obstructive pulmonary diseases, malaria, cigarette smoke, adipose tissue and its relationship with protein carbonylation Direct oxidation, glycoxidation and modifications by lipid peroxidation products as protein carbonylation pathways Emerging methods for characterizing carbonylated protein networks and affected metabolic pathways

12684.72 рублей

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Parvaiz Ahmad Water Stress and Crop Plants. A Sustainable Approach, 2 Volume Set

Plants are subjected to a variety of abiotic stresses such as drought, temperature, salinity, air pollution, heavy metals, UV radiations, etc. To survive under these harsh conditions plants are equipped with different resistance mechanisms which vary from species to species. Due to the environmental fluctuations agricultural and horticultural crops are often exposed to different environmental stresses leading to decreased yield and problems in the growth and development of the crops. Drought stress has been found to decrease the yield to an alarming rate of some important crops throughout the globe. During last few decades, lots of physiological and molecular works have been conducted under water stress in crop plants. Water Stress and Crop Plants: A Sustainable Approach presents an up-to-date in-depth coverage of drought and flooding stress in plants, including the types, causes and consequences on plant growth and development. It discusses the physiobiochemical, molecular and omic approaches, and responses of crop plants towards water stress. Topics include nutritional stress, oxidative stress, hormonal regulation, transgenic approaches, mitigation of water stress, approaches to sustainability, and modern tools and techniques to alleviate the water stress on crop yields. This practical book offers pragmatic guidance for scientists and researchers in plant biology, and agribusinesses and biotechnology companies dealing with agronomy and environment, to mitigate the negative effects of stress and improve yield under stress. The broad coverage also makes this a valuable guide enabling students to understand the physiological, biochemical, and molecular mechanisms of environmental stress in plants.

25747.68 рублей

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Frans Bruijn J.de Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, 2 Volume Set

Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.

39866.95 рублей

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Purito Крем Витаминный с Экстрактами Облепихи и Мандарина для Сияния Кожи Sea Buckthorn Vital 70 Cream, 50 мл

Sea Buckthorn Vital 70 Cream эффективно восстанавливает, увлажняет и тонизирует кожу. Обладает сильным антиоксидантным действием, мягко осветляет, помогает в борьбе с тусклым и серым цветом лица. Высококонцентрированный крем прекрасно помогает во время авитаминоза кожи, оздоравливает и замедляет процессы старения.

1609 рублей

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Hemingway Ernest The Old Man and the Sea

The Old Man and the Sea is Ernest Hemingway's epic parable of Life and the struggle to endure when everything seems against you. In a bid to end a streak of bad luck, Cuban fisherman Santiago sails his tiny skiff far out to sea and hooks a colossal marlin which he is determined to land... The Old Man and the Sea brought Hemingway the Pulitzer Prize and helped him win the Nobel Prize for Literature.

943 рублей

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Ari Kiev Mastering Trading Stress. Strategies for Maximizing Performance

In Mastering Trading Stress, author Ari Kiev—a psychiatrist who specializes in stress management and works extensively with traders—offers examples, transcripts of conversations, and personality profiles of real-life traders to illustrate how stress affects their ability to perform at their best. Drawing on his vast experience, Kiev describes a variety of practical techniques that can be used to handle destructive emotions and out-of-control feelings, including his “Most Basic” stress busters, and tells what to do if a breakdown should occur.

3211.82 рублей

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Hordur Kristinsson G. Antioxidants and Functional Components in Aquatic Foods

Antioxidants and Functional Components in Aquatic Foods compiles for the first time the past and present research done on pro and antioxidants in aquatic animals. The book addresses an area of extreme importance for aquatic foods, since lipid oxidation leads to such a large number of quality problems. Many of these problems are also seen in other muscle based foods, but are exaggerated in aquatic foods, so the book’s contents will be of great use and interest to other fields. Written by top researchers in the field, the book offers not only general overviews of lipid oxidation in aquatic foods and aquatic food pro and antioxidant systems, but also covers specifics and gives the latest information on the key pro and anti-oxidants derived from aquatic foods as well as some of the most recent and innovative means to control lipid oxidations in aquatic foods and food systems with fish oils. Coverage includes the latest research on the effects aquatic foods have on oxidative stress in the human body, an area of great interest recently. Additionally, a chapter is devoted to the latest techniques to measure antioxidative potential of aquatic foods, an area still in development and one very important to the antioxidant research community. Antioxidants and Functional Components in Aquatic Foods will be of great interest to the food science, medical, biochemical and pharmaceutical fields for professionals who deal with aquatic food products, muscle foods products (beef, pork, poultry etc), lipid oxidation, and pro-oxidant and antioxidant systems.

15891.3 рублей

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Crichton Robert Metal-Based Neurodegeneration. From Molecular Mechanisms to Therapeutic Strategies

Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings, including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides. Topics covered include: Brain function, physiology and the blood-brain barrier Immune system and neuroinflammation Aging and mild cognitive impairment, MCI Parkinson’s Disease Alzheimer’s Disease Creutzfelt-Jakob and related prion diseases Alcoholic Brain Damage Therapeutic strategies to combat the onset and progression of neurological diseases This extensively updated, full colour, second edition of Metal-based Neurodegeneration is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.

15972.32 рублей

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J. Bremner Douglas Posttraumatic Stress Disorder. From Neurobiology to Treatment

Posttraumatic Stress Disorder: From Neurobiology to Treatment presents a comprehensive look at this key neuropsychiatric disorder. The text examines the neurobiological basis of post-traumatic stress and how our understanding of the basic elements of the disease have informed and been translated into new and existing treatment options. The book begins with a section on animal models in posttraumatic stress disorder research, which has served as the basis of much of our neurobiological information. Chapters then delve into applications of the clinical neuroscience of posttraumatic stress disorder. The final part of the books explores treatments and how our basic and clinical research is now being converted into treatment. Taking a unique basic science to translational intervention approach, Posttraumatic Stress Disorder: From Neurobiology to Treatment is an invaluable resource for researchers, students and clinicians dealing with this complex disorder.

9419.5 рублей

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Riordan Rick Percy Jackson and Sea of Monster

Half Boy. Half God. ALL Hero. You can't tell by looking at me that my dad is Poseidon, God of the Sea. It's not easy being a half-blood these days. Even a simple game of dodgeball becomes a death match against an ugly gang of cannibal giants - and that was only the beginning. Now Camp Half-Blood is under attack, and unless I can get my hands on the Golden Fleece, the whole camp will be invaded by monsters. Big ones

679 рублей

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John Russell A. Neuroendocrinology of Stress

Exposure to chronic stress has cumulative adverse effects on physical and mental health, considered to be the consequence of chronic exposure to high levels of stress hormones. Consequently, there is extensive research in progress to investigate and better understand how the brain organises neuroendocrine stress responses and how interventions may be able to moderate these responses to improve mental and physical health. Neuroendocrinology of Stress highlights current knowledge of the organisation and physiology of these stress response systems, how the impact of dysregulation of these systems is being investigated, and considers the ways in which contributions to both psychiatric and physical diseases resulting from chronic stress effects can be critically addressed in basic research Written by a team of internationally renowned researchers, each chapter presents a succinct summary of the very latest developments in the field Both print and enhanced e-book versions are available Illustrated in full colour throughout This is the second volume in a new Series «Masterclass in Neuroendocrinology», a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Series Editors: John A. Russell, University of Edinburgh, UK and William E. Armstrong, The University of Tennessee, USA

7427.21 рублей

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Nadiya Hussain The Fall and Rise of the Amir Sisters

Heart-warming storytelling with strong themes of sisterhood from nation’s favourite and former Bake Off winner Nadiya Hussain, this is Little Women meets Marian Keyes’ Walsh family series for a new generation of readers.The four Amir Sisters – Fatima, Farah, Bubblee and Mae – are as close as sisters can be but sometimes even those bonds can be pushed to their limits . . .Becoming a mother has always been Farah’s dream so when older sister Fatima struggles with a tough pregnancy whilst Farah has trouble conceiving she cant help but be jealous. Until a plan to break a huge cultural taboo in her family, and use a surrogate gives her a renewed hope. But nothing is ever that easy in this warm, witty look at a modern British family.

1311.09 рублей

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Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.

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