saeed khan human immunodeficiency virus and human papilloma virus in pakistan

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Dashner James The Kill Order

Read after The Maze Runner, The Scorch Trials and The Death Cure ...When sun flares hit the Earth, intense heat, toxic radiation and flooding followed, wiping out much of the human race. Those who survived live in basic communities in the mountains, hunting for food. For Mark and his friends, surviving is difficult, and then an enemy arrives, infecting people with a highly contagious virus. Thousands die, and the virus is spreading. Worse, it's mutating, and people are going crazy. It's up to Mark and his friends to find the enemy - and a cure - before the Flare infects them all ...

1154 рублей

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Brian Henderson The Human Microbiota and Chronic Disease. Dysbiosis as a Cause of Human Pathology

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

11243.68 рублей

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Ashutosh Tiwari Advanced Molecularly Imprinting Materials

Molecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications. In this book, the chapters are clustered into two main sections: Strategies to be employed when using the affinity materials, and rational design of MIPs for advanced applications. In the first part, the book covers the recent advances in producing MIPs for sample design, preparation and characterizations. In the second part, the chapters demonstrate the importance and novelty of creation of recognition imprinted on the materials and surfaces for a range of microbial detection sensors in the biomedical, environmental and food safety fields as well as sensing human odor and virus monitoring systems. Part 1: Strategies of affinity materials Molecularly imprinted polymers MIP nanomaterials Micro- and nanotraps for solid phase extraction Carbonaceous affinity nanomaterials Fluorescent MIPs MIP-based fiber optic sensors Part 2: Rational design of MIP for advanced applications MIP-based biomedical and environmental sensors Affinity adsorbents for environmental biotechnology MIP in food safety MIP-based virus monitoring MIP-based drug delivery and controlled release Biorecognition imprints on the biosensor surfaces MIP-based sensing of volatile organic compounds in human body odour MIP-based microcantilever sensor system

16871.56 рублей

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Thomas Braciale J. Textbook of Influenza

The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.

17921.59 рублей

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Anne Bridgen Reverse Genetics of RNA Viruses. Applications and Perspectives

Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.

12368.4 рублей

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Sunit Singh Kumar Sexually Transmitted Diseases

Comprehensively explores sexually transmitted diseases, from epidemiology, causative pathogens, clinical impact, and immunology, to management strategies utilizing new strategies of genomics and next-generation diagnostic tools Sexually transmitted infections (STI) are very common worldwide. More than 20 different STIs have been identified, and about 19 million men and women are infected each year in the United States alone. This book looks at the complete picture of common STIs— how they form, evolve, and transmit, as well as how they can be treated and managed with modern techniques, medicines, and tools. Diagnostics to Pathogenomics of Sexually Transmitted Infections runs the spectrum of discussion ranging from introduction of causative pathogen, their pathogenesis to epidemiology, immunology, to anatomy and physiology of human genitalia and management strategies. The book offers in-depth chapter coverage on effect of probiotics on reproductive health; mucosal immunity in sexually transmitted infections; the role of circumcision in preventing STIs; Human Immunodeficiency Virus (HIV); genital herpes; molluscum contagiosum; genital warts; chlaymydia trachomatis; donovanosis; gonorrhoea; treponematoses; genital mycoplasms; bacterial vaginosis; vulvovaginal candidiasis; chlaymydia; scabies; chancroid, yeast infections; and more. Comprehensively compiles most of the major sexually transmitted infections Presents updated information on clinical aspects of sexually transmitted infections Examines the priorities in pathogenesis of human sexually transmitted infections and discusses new strategies of genomics and next-generation diagnostic tools used for detection of such pathogens Explores the future of rapid molecular diagnostic techniques and the challenges posed in the diagnosis of human STIs Includes bench to bedside content that will appeal to both basic and clinical researchers By offering the latest knowledge about recent advances in sexually transmitted infections in an interdisciplinary fashion, Diagnostics to Pathogenomics of Sexually Transmitted Infections is the perfect book for virologists, microbiologists, infectious disease experts, vaccinologists, biomedical researchers, clinicians, pharmacologists, and public health specialists.

12771.36 рублей

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David Fredricks N. The Human Microbiota. How Microbial Communities Affect Health and Disease

The Human Microbiota offers a comprehensive review of all human-associated microbial niches in a single volume, focusing on what modern tools in molecular microbiology are revealing about human microbiota, and how specific microbial communities can be associated with either beneficial effects or diseases. An excellent resource for microbiologists, physicians, infectious disease specialists, and others in the field, the book describes the latest research findings and evaluates the most innovative research approaches and technologies. Perspectives from pioneers in human microbial ecology are provided throughout.

10954.54 рублей

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Niamh Reilly Women's Human Rights

Women's Human Rights: Seeking Gender Justice in a Globalising Age explores the emergence of transnational, UN-oriented, feminist advocacy for womens human rights, especially over the past three decades. It identifies the main feminist influences that have shaped the movement liberal, radical, third world and cosmopolitan and exposes how the Western, legalist, state-centric, and liberal biases of mainstream human rights discourse impede the realisation of human rights in womens lives everywhere. The book traces the evolution of the womens human rights movement through an examination of its key issues, debates, and practical interventions in international law and policy arenas. This includes efforts to: Develop global gender equality norms via the UN Womens Convention Frame violence against women as a human rights issue Address gender-based crimes in conflict situations, include women in conflict resolution and post-conflict reconstruction, and challenge new forms of militarism Highlight the gendered human rights dimensions of widening inequalities in a context of neo-liberal globalisation Develop human rights responses to anti-feminist fundamentalist movements with a focus on reproductive and sexual rights Ultimately, Women's Human Rights reaffirms a commitment to critically reinterpreted universal human rights principles and demonstrates the vital role that bottom-up, transnational movements play in making them a reality in women's lives.

5360.41 рублей

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Patrick Millot Designing Human-machine Cooperation Systems

This book, on the ergonomics of human−machine systems, is aimed at engineers specializing in informatics, automation, production or robotics, who are faced with a significant dilemma during the conception of human−machine systems. On the one hand, the human operator guarantees the reliability of the system and has been known to salvage numerous critical situations through an ability to reason in unplanned, imprecise and uncertain situations; on the other hand, the human operator can be unpredictable and create disturbances in the automated system. The first part of the book is dedicated to the methods of human-centered design, from three different points of view, the various chapters focusing on models developed by human engineers and functional models to explain human behavior in their environment, models of cognitive psychology and models in the domain of automobile driving. Part 2 develops the methods of evaluation of the human−machine systems, looking at the evaluation of the activity of the human operator at work and human error analysis methods. Finally, Part 3 is dedicated to human−machine cooperation, where the authors show that a cooperative agent comprises a know-how and a so-called know-how-to-cooperate and show the way to design and evaluate that cooperation in real industrial contexts.

14321.19 рублей

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Uversky Vladimir Flexible Viruses. Structural Disorder in Viral Proteins

This book provides up-to-date information on experimental and computational characterization of the structural and functional properties of viral proteins, which are widely involved in regulatory and signaling processes. With chapters by leading research groups, it features current information on the structural and functional roles of intrinsic disorders in viral proteomes. It systematically addresses the measles, HIV, influenza, potato virus, forest virus, bovine virus, hepatitis, and rotavirus as well as viral genomics. After analyzing the unique features of each class of viral proteins, future directions for research and disease management are presented.

13100.24 рублей

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Advanced Life Support Group (ALSG) Human Factors in the Health Care Setting. A Pocket Guide for Clinical Instructors

Human factors relates to the interaction of humans and technical systems. Human factors engineering analyzes tasks, considering the components in relation to a number of factors focusing particularly on human interactions and the interface between people working within systems. This book will help instructors teach the topic of human factors.

2599.2 рублей

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Jeang Kuan-Teh Viral Oncology. Basic Science and Clinical Applications

A comprehensive look at the latest research findings and clinical applications of oncogenic viruses Written by a panel of academic experts, Viral Oncology is the first self-contained and comprehensive book to present both scientific and clinical information on viruses linked to some of the most important human cancers. Readers can turn to this book for the most in-depth and up-to-date coverage of: HPV-associated cancers; molecular events associated with HPV-induced human cancer; the role of the HPV E6 oncoprotein in malignant progression; virus association with brain tumors; involvement of the polyomavirus JCV in colorectal cancer; possibleassociation of BKV with prostate cancer; oncogenic transformation bypolyomavirus large T antigen; SV40 and human cancer; SV40 and mesothelioma; molecular immunology of hepatitis B–associated viral cancer; hepatitis B vaccine and hepatocellular carcinoma; pathogenesis of acute and chronic hepatitis Cvirus infection; molecular mechanisms of hepatitis C virus-induced cellulartransformation; clinical aspects of HTLV-1 associated cancer; oncogenic potential of the HTLV-1 tax protein; HIV-associated malignancy; HIV-related lymphoma; biology and epidemiology of HHV-8; the role of KSHV in pathogenesis of Kaposi'ssarcoma; molecular pathobiology of EBV infection; and EBV as a pathogen. Several chapters are devoted to the basic science of oncogenic viruses for thestudy of their pathogenesis, drug development, and employment of viral vectorsfor vaccine and gene therapy. The book also includes complementary clinically based chapters describing natural courses and treatments. Additionally, bonusclinical materials are embedded within chapters and an easy-to-use indexcompletes the book. Viral Oncology is an essential resource for clinical and research oncologists in medical facilities and biological research laboratories; clinicians and scientists working in related biomedical areas; medical students working toward a first or higher degree in the life sciences and other biomedical fields; and pharmaceutical scientists and developers.

14632.88 рублей

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William J. Rothwell The Encyclopedia of Human Resource Management, Volume 3

The three volumes in The Encyclopedia of Human Resource Management offer a comprehensive review of the essential issues and most important information available on the topic. Each volume in the encyclopedia contains contributions from some of the most celebrated names in the field of human resource management (HRM) and addresses the myriad challenges faced by today's human resource professionals. Volume 3 highlights three main topics HR professionals have identified as critical issues in today's workplace: Leadership and Learning; Strategy and Measurement; and The Evolution of Human Resources. Many of the articles in this volume provide an in-depth discussion of a current human resource topic while others introduce a new way of approaching a familiar HR challenge. Each article is designed to stimulate critical thinking and reflection. The topics covered include: Best Practices in Leadership Development; Leadership is Going Global; Web 2.0 Applications in Corporate Training; The Social Construction of Productive Organizations; Leadership Versatility; Strategy and Measurement; Strategic Business Partner Role; Human Resource Metrics; The HR Transition to Strategic Partner; Workplace Bullying; Lost Wisdom, Lost ROI; The Role of HR in Fostering Innovation in Organizations; Closing Critical Skills Gaps; Employee Engagement and Corporate Social Responsibility; The Implications of Situational Strength for HRM; and more. The Encyclopedia of Human Resource Management gives human resource professionals the knowledge, information, and tools needed to implement the best practices in the field.

14096.46 рублей

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Christian Bernard Ist es möglich, Genotyp 1b vollständig zu heilen? Wie viele Jahre leben mit Hepatitis C

Dennoch wird ein solcher Virus «Japaner» genannt, weil seine Heimatländer Japan, Taiwan und China sind. In einigen Berichten heißt es, das Mutterland dieses Virus sei der ferne Osten Russlands…

196 рублей

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Christian Bernard Is it possible to completely cure genotype 1b. How many years live with hepatitis C

Still, such a virus is called “Japanese”, because its native countries are Japan, Taiwan and China. Some reports state that the motherland of this virus is Far East Russia…

296 рублей

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Tex Crampin Human Factors in Control Room Design. A Practical Guide for Project Managers and Senior Engineers

A succinct guide to a Human Factors programme of work This book provides a reference for project managers to assist in identifying the key rudiments of good Human Factors design. It is intended to be used in conjunction with an appointed Human Factors manager as part of a detailed design programme, read by all engineers and designers in order to establish a wide understanding across the whole team of the importance of Human Factors. Human Factors in Military and Industrial Control Room Design offers succinct advice, tailored for rapid injection into complex Human Factors programmes, together with applicability to any control room design, military or industrial. Applications include warship control rooms, command centres, fire and accident response centres, chemical plants, nuclear installations, oil rigs, refineries and other similar industries. Key features: A template for a thorough Human Factors programme of work. Applicability to any control room design. Aims to address operator workload and optimise system performance, comfort and safety. Can save significant costs by optimised system integration and enhanced system operation. It is advised that project managers use Human Factors in Military and Industrial Control Room Design as a template to develop a control room «Operating Philosophy» and «Human Computer Interface (HCI) Style Guide» for their own purposes within the constraints of their specific industry.

9498.54 рублей

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Christophe Kolski Human-Computer Interactions in Transport

The human-computer interactions are more and more present in our everyday life, and lead to many conceptual and methodological problems for the designers and evaluators of interactive systems. This book is about Human-Computer Interaction in Transport domain, in which the traveler becomes a user of information systems, particularly before and during the travel(s). This book will focus on traveler information and personalized systems, using a human-centered design approach.

12644.28 рублей

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Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

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