rahul deshmukh mayank prabhakar and puneet kumar cb1 receptor modulation against parkinson’s disease in rats

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Ahmed Moustafa A. Computational Models of Brain and Behavior

A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

11247.23 рублей

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Leff Todd Adipose Tissue in Health and Disease

This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

20993.34 рублей

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Zhechen Zhu Automatic Modulation Classification. Principles, Algorithms and Applications

Automatic Modulation Classification (AMC) has been a key technology in many military, security, and civilian telecommunication applications for decades. In military and security applications, modulation often serves as another level of encryption; in modern civilian applications, multiple modulation types can be employed by a signal transmitter to control the data rate and link reliability. This book offers comprehensive documentation of AMC models, algorithms and implementations for successful modulation recognition. It provides an invaluable theoretical and numerical comparison of AMC algorithms, as well as guidance on state-of-the-art classification designs with specific military and civilian applications in mind. Key Features: Provides an important collection of AMC algorithms in five major categories, from likelihood-based classifiers and distribution-test-based classifiers to feature-based classifiers, machine learning assisted classifiers and blind modulation classifiers Lists detailed implementation for each algorithm based on a unified theoretical background and a comprehensive theoretical and numerical performance comparison Gives clear guidance for the design of specific automatic modulation classifiers for different practical applications in both civilian and military communication systems Includes a MATLAB toolbox on a companion website offering the implementation of a selection of methods discussed in the book

9298 рублей

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Mylène Pischella Digital Communications 2. Digital Modulations

This second volume covers the following blocks in the chain of communication: the modulation baseband and transposed band, synchronization and channel estimation as well as detection. Variants of these blocks, the multicarrier modulation and coded modulations are used in current systems or future.

10497.42 рублей

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James Fingeroth Advances in Intervertebral Disc Disease in Dogs and Cats

Advances in Intervertebral Disc Disease in Dogs and Cats defines our present knowledge of this common clinical problem, compiling information related to the canine and feline intervertebral disc into a single resource. As a comprehensive, focused work, the book is an authoritative reference for understanding and treating disc disease, providing a sound scientific and clinical basis for decision making. Offering an objective synthesis of the current literature, the book supplies guidance on the approach to a potential disc rupture, surgical and medical strategies, and management of the patient. Offering a complete understanding of intervertebral disc disease, the book describes and discusses the controversies and issues surrounding this topic, acknowledging the gaps in our knowledge. Advances in Intervertebral Disc Disease in Dogs and Cats presents up-to-date, reliable information on this common condition for veterinary surgeons, neurologists, and general practitioners.

9672.19 рублей

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Lindsey Snyder B.C. Canine and Feline Anesthesia and Co-Existing Disease

Canine and Feline Anesthesia and Co-Existing Disease is the first book to draw together clinically relevant information on the anesthetic management of dogs and cats with existing disease conditions. Providing a detailed reference on avoiding and managing complications resulting from concurrent disease, the book offers a ready reference for handling anesthesia in patients with common presenting diseases. Organized by body system, Canine and Feline Anesthesia and Co-Existing Disease is designed to allow the reader to quickly find and apply advice for anesthetizing patients with specific conditions. Each chapter presents in-depth, practical information on the special considerations before, during, and after sedation and anesthesia of a patient with a given disease. Canine and Feline Anesthesia and Co-Existing Disease is a useful reference for general practitioners, veterinary students, specialists in a variety of areas, and veterinary anesthesiologists alike.

7722.25 рублей

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Stephen Barthold W. Pathology of Laboratory Rodents and Rabbits

Now in its fourth edition, Pathology of Laboratory Rodents and Rabbits has become a standard text for veterinary pathologists, laboratory animal veterinarians, students, and others interested in these species. • The standard reference on the pathogenesis and cardinal diagnostic features of diseases of mice, rats, hamsters, gerbils, guinea pigs, and rabbits • Expanded coverage of rabbit disease, normal anatomic features, and biology • Over 450 color photographs illustrating gross and microscopic pathology • Companion website offering images from the text in PowerPoint

11246.52 рублей

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George Stouffer A. Cardiovascular Hemodynamics for the Clinician

Cardiovascular Hemodynamics for the Clinician, 2nd Edition, provides a useful, succinct and understandable guide to the practical application of hemodynamics in clinical medicine for all trainees and clinicians in the field. Concise handbook to help both practicing and prospective clinicians better understand and interpret the hemodynamic data used to make specific diagnoses and monitor ongoing therapy Numerous pressure tracings throughout the book reinforce the text by demonstrating what will be seen in daily practice Topics include coronary artery disease; cardiomyopathies; valvular heart disease; arrhythmias; hemodynamic support devices and pericardial disease New chapters on TAVR, ventricular assist devices, and pulmonic valve disease, expanded coverage of pulmonary hypertension, fractional flow reserve, heart failure with preserved ejection fraction and valvular heart disease Provides a basic overview of circulatory physiology and cardiac function followed by detailed discussion of pathophysiological changes in various disease states

4404.99 рублей

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Kellyann Petrucci Boosting Your Immunity For Dummies

Boost your body's natural defenses against disease Good nutrition is a key weapon against colds and the flu. The foods, supplements, and practices outlined in Boosting Your Immunity For Dummies can boost your body's natural defenses against disease when they're incorporated into your daily diet and lifestyle. Boosting Your Immunity For Dummies provides hands-on techniques for supercharging your immune system to resist illness and prevent disease. Through diet, exercise, stress reduction, and nutritional supplements, the role of water, sunlight, and oxygen, you can harness the power of your immune system and help your body combat health issues that include: antibiotic-resistant bacteria, allergies, Hepatitis C, pre-menopause, menopause, cancer, Rheumatoid arthritis, dental, and autoimmune diseases. In addition, Boosting Your Immunity For Dummies includes tasty recipes for every meal of the day along with shopping lists and tips for stretching grocery dollars while still eating healthy! Expert advice and tips on living and eating healthy Includes more than 40 healthy and tasty immunity boosting recipes Shows you how to supercharge your immune system If you're looking for a resource that will help you improve your overall health by eating properly and exercising to drastically improve their immunity to disease, Boosting Your Immunity For Dummies has you covered.

1465.86 рублей

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John Iskander Concepts and Methods in Infectious Disease Surveillance

Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health’s experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.

7195.1 рублей

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Simon Stewart The Heart of Africa. Clinical Profile of an Evolving Burden of Heart Disease in Africa

While many high-income countries observe a relative decline in the population impact of heart disease and deal with the problem of an older patient population who readily survive earlier non-fatal encounters with the condition, Africa contends with a typically younger population with frequently advanced and often fatal heart disease. While high-income countries exclusively deal with non-communicable forms of heart disease, Africa contends with both communicable and non-communicable forms of heart disease. Designed to provide anyone with an interest in heart disease in Africa with an immediate sense of how the area is progressing from a clinical to research perspective in responding to this evolving epidemic Presents salient research uncovering the evolving burden of communicable and non-communicable forms of heart disease, Includes content on maternal heart disease, infant and childhood heart disease, risk and prevention, heart failure and other common forms of heart disease in rural and urban communities in Africa.

2048.83 рублей

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Vaidya Vishal S. Biomarkers. In Medicine, Drug Discovery, and Environmental Health

This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.

13947.02 рублей

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David Lillicrap Von Willebrand Disease. Basic and Clinical Aspects

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding. Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy. Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

11468.48 рублей

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Raz Jelinek Lipids and Cellular Membranes in Amyloid Diseases

Addressing one of the biggest riddles in current molecular cell biology, this ground-breaking monograph builds the case for the crucial involvement of lipids and membranes in the formation of amyloid deposits. Tying together recent knowledge from in vitro and in vivo studes, and built on a sound biophysical and biochemical foundation, this overview brings the reader up to date with current models of the interplay between membranes and amyloid formation. Required reading for any researcher interested in amyloid formation and amyloid toxicity, and possible avenues for the prevention or treatment of neurodegenerative disorders. From the contents: * Interactions of Alpha-Synuclein with Lipids * Interaction of hIAPP and its Precursors with Membranes * Amyloid Polymorphisms: Structural Basis and Significance in Biology and Molecular Medicine * The Role of Lipid Rafts in Alzheimer's Disease * Alzheimer's Disease as a Membrane-Associated Enzymopathy of Beta-Amyloid Precursor Protein (APP) Secretases * Impaired Regulation of Glutamate Receptor Channels and Signaling Molecules by Beta-Amyloid in Alzheimer's Disease * Membrane Changes in BSE and Scrapie * Experimental Approaches and Technical Challenges for Studying Amyloid-Membrane Interactions and more

15096.5 рублей

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Tim Storr Ligand Design in Medicinal Inorganic Chemistry

Increasing the potency of therapeutic compounds, while limiting side-effects, is a common goal in medicinal chemistry. Ligands that effectively bind metal ions and also include specific features to enhance targeting, reporting, and overall efficacy are driving innovation in areas of disease diagnosis and therapy. Ligand Design in Medicinal Inorganic Chemistry presents the state-of-the-art in ligand design for medicinal inorganic chemistry applications. Each individual chapter describes and explores the application of compounds that either target a disease site, or are activated by a disease-specific biological process. Ligand design is discussed in the following areas: Platinum, Ruthenium, and Gold-containing anticancer agents Emissive metal-based optical probes Metal-based antimalarial agents Metal overload disorders Modulation of metal-protein interactions in neurodegenerative diseases Photoactivatable metal complexes and their use in biology and medicine Radiodiagnostic agents and Magnetic Resonance Imaging (MRI) agents Carbohydrate-containing ligands and Schiff-base ligands in Medicinal Inorganic Chemistry Metalloprotein inhibitors Ligand Design in Medicinal Inorganic Chemistry provides graduate students, industrial chemists and academic researchers with a launching pad for new research in medicinal chemistry.

14622.12 рублей

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Louis-Michel Wong Kee Song Endoscopy in Liver Disease

Liver disease is an increasingly common cause of mortality, and its management is often complex and challenging. Endoscopy has in recent times undergone a period of rapid progress, with numerous novel and specialized endoscopic modalities that are of increasing value in the investigation and management of the patient with liver disease. As the technology in endoscopy expands, both as a diagnostic and interventional procedure, so does the role of the endoscopist in liver disease. This full colour book and companion website offer a comprehensive guidance as to when, why, and how to perform endoscopy to best manage your patients. Brings together two key areas – liver disease and endoscopy – into one expert clinical textbook Covers the entire spectrum of clinical problems that gastroenterologists and endoscopists face while managing patients with liver disease Includes the latest management guidelines from the key international societies, such as the ASGE, AASLD, EASL and BSG Well illustrated with over 150 high-quality colour images 11 high-quality videos illustrating optimum endoscopy practice, all clearly referenced in the text An indispensable tool for all gastroenterologists, hepatologists and endoscopists, Endoscopy in Liver Disease is perfect for learning how to perform endoscopy safely and effectively in the patient population with liver disorders.

13052.77 рублей

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Undurti Das N. Metabolic Syndrome Pathophysiology. The Role of Essential Fatty Acids

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.

17167.5 рублей

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Infectious disease surveillance has evolved at an extraordinary pace during the past several decades, and continues to do so. It is increasingly used to inform public health practice in addition to its use as a tool for early detection of epidemics. It is therefore crucial that students of public health and epidemiology have a sound understanding of the concepts and principles that underpin modern surveillance of infectious disease. Written by leaders in the field, who have vast hands-on experience in conducting surveillance and teaching applied public health, Concepts and Methods in Infectious Disease Surveillance is comprised of four sections. The first section provides an overview, a description of systems used by public health jurisdictions in the United States and legal considerations for surveillance. The second section presents chapters on major program-area or disease-specific surveillance systems, including those that monitor bacterial infections, foodborne diseases, healthcare-associated infections, and HIV/AIDS. The following section is devoted to methods for conducting surveillance and also approaches for data analysis. A concluding section summarizes communication of surveillance findings, including the use of traditional and social media, in addition to showcasing lessons learned from the New York City Department of Health’s experience in surveillance and epidemiology training. This comprehensive new book covers major topics at an introductory to intermediate level, and will be an excellent resource for instructors. Suitable for use in graduate level courses in public health, human and veterinary medicine, and in undergraduate programs in public-health-oriented disciplines, Concepts and Methods in Infectious Disease Surveillance is also a useful primer for frontline public health practitioners, hospital epidemiologists, infection control practitioners, laboratorians in public health settings, infectious disease researchers, and medical and public health informaticians interested in a concise overview of infectious disease surveillance.

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