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Vikash Babu Biofuels Production

The search for alternative sources of energy to offset diminishing resources of easy and cost-effective fossil fuels has become a global initiative, and fuel generated from biomass is a leading competitor in this arena. Large-scale introduction of biofuels into the energy mix could contribute to environmentally and economicaly sustainable development on a global scale. The processes and methodologies presented in this volume will offer a cutting-edge and comprehensive approach to the production of biofuels, for engineers, researchers, and students.

15069.52 рублей

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Findlay John W. Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.

10713.33 рублей

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Elke Schmidt Asymmetric Catalysis on Industrial Scale

Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates. In so doing, it is equally a source of information and inspiration for academic research, and, with its contribution by Noble prizewinner W. S. Knowles, will also heighten the status of industrial catalyst specialists working in the exciting field of enantioselective catalysis. Some 25 contributions from top industrial researchers around the world present case studies on the development of the widest possible range of large-scale enantioselective processes, featuring stereoselective production processes of fine-chemicals, agrochemicals and pharmaceuticals. Clearly structured according to the nature of the task, this handbook adopts a problem-driven approach such that readers can easily find how colleagues have dealt with a similar situation.

20661.42 рублей

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Hsien-Hsin Tung Crystallization of Organic Compounds. An Industrial Perspective

Filled with industrial examples emphasizing the practical applications of crystallization methodologies Based on the authors' hands-on experiences as process engineers at Merck, Crystallization of Organic Compounds guides readers through the practical aspects of crystallization. It uses plenty of case studies and examples of crystallization processes, ranging from development through manufacturing scale-up. The book not only emphasizes strategies that have been proven successful, it also helps readers avoid common pitfalls that can render standard procedures unsuccessful. The goal of this text is twofold: Build a deeper understanding of the fundamental properties of crystallization as well as the impact of these properties on crystallization process development. Improve readers' problem-solving abilities by using actual industrial examples with real process constraints. Crystallization of Organic Compounds begins with detailed discussions of fundamental thermodynamic properties, nucleation and crystal growth kinetics, process dynamics, and scale-up considerations. Next, it investigates modes of operation, including cooling, evaporation, anti-solvent, and reactive crystallization. The authors conclude with special applications such as ultrasound in crystallization and computational fluid dynamics in crystallization. Most chapters feature multiple examples that guide readers step by step through the crystallization of active pharmaceutical ingredients (APIs). With its focus on industrial applications, this book is recommended for chemical engineers and chemists who are involved with the development, scale-up, or operation of crystallization processes in the pharmaceutical and fine chemical industries.

9321.38 рублей

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Harmsen J. Sustainable Development in the Process Industries. Cases and Impact

The complete, hands-on guide to sustainable development Today's process industries must develop natural resources within an eco-friendly framework that balances current demand with future need. Realizing this goal necessitates global vigilance of three key areas—people, planet, and prosperity—known as the Triple Bottom Line or, simply, the Triple P. Sustainable Development in the Process Industries details how worldwide implementation of sustainable processes in present-day industries can positively influence the Triple P going forward by lowering poverty, reducing pollution, and conserving resources. This in-depth guide includes: Real-world case studies and examples Individual chapters written by industry experts Application in industries such as petroleum and fuel, food, recycling, mineral processing, and water processing Focus on the micro (molecules, unit operations, processes) to the macro (industrial sites, value chains, regions, the world) Providing lessons with practical application rather than pure theory, Sustainable Development in the Process Industries offers sound solutions to social, ecological, and economic challenges imperative to assuring our planet's well-being for generations.

8413.79 рублей

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Mike Lee S. Oral Bioavailability Assessment. Basics and Strategies for Drug Discovery and Development

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development. • Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability • Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development • Explains how preclinical animal models – used in preclinical testing – and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development • Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS) • Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development

12743.32 рублей

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Vijay Thakur Kumar Surface Modification of Biopolymers

This book addresses surface modification techniques, which are critical for tailoring and broadening the applications of naturally occurring biopolymers. Biopolymers represent a sustainable solution to the need for new materials in the auto, waste removal, biomedical device, building material, defense, and paper industries. Features: First comprehensive summary of biopolymer modification methods to enhance compatibility, flexibility, enhanced physicochemical properties, thermal stability, impact response, and rigidity, among others Address of a green, eco-friendly materials that is increasing in use, underscoring the roles of material scientists in the future of new «green» bioolymer material use Coverage applications in automotive development, hazardous waste removal, biomedical engineering, pulp and paper industries, development of new building materials, and defense-related technologies Facilitation of technology transfer

11283.48 рублей

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Vikas Mittal Hybrid Nanomaterials. Advances in Energy, Environment, and Polymer Nanocomposites

A hybrid material is defined as a material composed of an intimate mixture of inorganic components, organic components, or both types of components. In the last few years, a tremendous amount of attention has been given towards the development of materials for efficient energy harvesting; nanostructured hybrid materials have also been gaining significant advances to provide pollutant free drinking water, sensing of environmental pollutants, energy storage and conservation. Separately, intensive work on high performing polymer nanocomposites for applications in the automotive, aerospace and construction industries has been carried out, but the aggregation of many fillers, such as clay, LDH, CNT, graphene, represented a major barrier in their development. Only very recently has this problem been overcome by fabrication and applications of 3D hybrid nanomaterials as nanofillers in a variety of polymers. This book, Hybrid Nanomaterials, examines all the recent developments in the research and specially covers the following subjects: Hybrid nanostructured materials for development of advanced lithium batteries High performing hybrid nanomaterials for supercapacitor applications Nanohybrid materials in the development of solar energy applications Application of hybrid nanomaterials in water purification Advanced nanostructured materials in electromagnetic shielding of radiations Preparation, properties and application of hybrid nanomaterials in sensing of environmental pollutants Development of hybrid fillers/polymer nanocomposites for electronic applications High performance hybrid filler reinforced epoxy nanocomposites State-of-the-art overview of elastomer/hybrid filler nanocomposites

16384.96 рублей

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Stanley Weiss I. Product and Systems Development. A Value Approach

A thorough treatment of product and systems development in terms of value to all stakeholders Product and Systems Development compiles more than twenty years of research and practice from a value perspective, from vision and marketing to design, manufacturing, delivery, operations, and maintenance. It defines stakeholder value and identifies specific stakeholders in the product and system development process; covers best practices in development; and examines systems engineering, current industry views, and the life cycle of a value stream. Featuring appendices written by professionals in the field on topics such as Design Structure Matrices, Lean Enablers for systems engineering, and MDAO and simulations, this indispensable guide: Explains why stakeholders' values can hold the key to fulfillment or defeat of the developer's vision Emphasizes the succession of value-contributing practices and tools that form a framework for development success Integrates the technical, productivity, and customer/end-user elements in product and system development Uses more than 100 tables and figures to illustrate the above processes, as well as corollary elements of risk, failure analysis, and fault-tolerant design Includes numerous case studies and links to online material Product and Systems Development is an excellent coursebook for senior and graduate students in aerospace, mechanical, civil, electrical, and material engineering, as well as management science and engineering. It is also a useful reference for practicing engineers in a variety of technology-based industries.

7725.07 рублей

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Ganapathy Subramanian Biopharmaceutical Production Technology, 2 Volume Set

Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their manufacturing processes. This two volume handbook systematically addresses the key steps and challenges in the production process and provides valuable information for medium to large scale producers of biopharmaceuticals. It is divided into seven major parts: – Upstream Technologies – Protein Recovery – Advances in Process Development – Analytical Technologies – Quality Control – Process Design and Management – Changing Face of Processing With contributions by around 40 experts from academia as well as small and large biopharmaceutical companies, this unique handbook is full of first-hand knowledge on how to produce biopharmaceuticals in a cost-effective and quality-controlled manner.

42853.31 рублей

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Alireza Bahadori Corrosion and Materials Selection. A Guide for the Chemical and Petroleum Industries

The petroleum and chemical industries contain a wide variety of corrosive environments, many of which are unique to these industries. Oil and gas production operations consume a tremendous amount of iron and steel pipe, tubing, pumps, valves, and sucker rods. Metallic corrosion is costly. However, the cost of corrosion is not just financial. Beyond the huge direct outlay of funds to repair or replace corroded structures are the indirect costs – natural resources, potential hazards, and lost opportunity. Wasting natural resources is a direct contradiction to the growing need for sustainable development. By selecting the correct material and applying proper corrosion protection methods, these costs can be reduced, or even eliminated. This book provides a minimum design requirement for consideration when designing systems in order to prevent or control corrosion damage safely and economically, and addresses: • Corrosion problems in petroleum and chemical industries • Requirements for corrosion control • Chemical control of corrosive environments • Corrosion inhibitors in refineries and petrochemical plants • Materials selection and service life of materials • Surface preparation, protection and maintainability • Corrosion monitoring – plant inspection techniques and laboratory corrosion testing techniques Intended for engineers and industry personnel working in the petroleum and chemical industries, this book is also a valuable resource for research and development teams, safety engineers, corrosion specialists and researchers in chemical engineering, engineering and materials science.

17622.33 рублей

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Kenneth Kahn B. The PDMA Handbook of New Product Development

New Product Development is one of the most important challenges facing organizations today. The Product Development and Management Association (PDMA) Handbook of New Product Development 3rd Edition provides an exceptional review of cutting edge topics for both new and experienced product development leaders. It offers a comprehensive and updated guide to the practices, processes and tools critical to achieving and sustaining new product/service development success in today’s world, delivering valuable information about the fundamentals as well as emerging practices such as venturing, virtual product development and the use of social media in NPD. As the premier global advocate for professionals and organizations working in the fields of new product/service development, PDMA has assembled in the Handbook unique content on the critical aspects of product development success including its 2012 Best Practices Research, Lessons Learned from its Outstanding Corporate Innovator Award Winners and keys to success from organizations with proven innovation track records. The 3rd Edition is an essential reference for anyone with responsibility for product development activities, from novices looking for fundamentals to experts seeking insights on emerging concepts, and is relevant for all functions and all product/service industries.

10330.71 рублей

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Noha Mellor Arab Media. Globalization and Emerging Media Industries

This book provides a clear and authoritative introduction to the emerging Arab media industries in the context of globalization and its impacts, with a focus on publishing, press, broadcasting, cinema and new media. Through detailed discussions of the regulation and economics of these industries, the authors argue that the political, technological and cultural changes on the global media scene have resulted in the reorganization of the Arab media field. They provide striking examples of this through the particular effects on media policies, media technology and the content and genres developed for the new generation of media consumers. As part of the book's overview of the contemporary characteristics of Arab media, the authors outline the development of the role of modern Arab media from a tool of mobilizing the public to a tool of commercial and symbolic profit. Overall, the volume illustrates how the Arab region represents a unique case where the commercialization and liberalization of selected media industries has gone hand in hand with continuous state intervention and an increasing self censorship. Written for students without prior knowledge of the topic, Arab Media will be essential reading for all interested in the contemporary global media industries.

5093.87 рублей

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Kim Ekroos Lipidomics. Technologies and Applications

Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipid analysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as well as within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical instruments and techniques, allowing them to provide here first-hand practical experience for newcomers to the field. The first half of the book covers current methodologies, ranging from global to targeted lipidomics and shotgun approaches, while the second part discusses the role of lipidomics in biomedical and pharmaceutical research, covering such diverse fields as inflammation, metabolic syndrome, cardiovascular and neurological disease. Both small and large-scale, high-throughput approaches are discussed, resulting in an invaluable source for academic and industrial research and development.

9831.25 рублей

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Mrityunjay Singh Design, Development, and Applications of Engineering Ceramics and Composites

This compilation of proceedings covering the latest scientific and technological developments in design, development, and applications of engineering ceramics and composites provides a useful one-stop resource for understanding the most important issues in design, development, and applications of engineering ceramics and composites. Logically organized and carefully selected articles give insight into design, development, and applications of engineering ceramics and composites and incorporates the latest developments related to design, development, and applications of engineering ceramics and composites including developments in engineering ceramics, advanced ceramic coatings, and geopolymers.

8884.05 рублей

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Ekins Sean Pharmaceutical Data Mining. Approaches and Applications for Drug Discovery

Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.

12243.8 рублей

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Patrizia Lombardi Future Challenges in Evaluating and Managing Sustainable Development in the Built Environment

Future Challenges in Sustainable Development within the Built Environment stimulates and reinterprets the demands of Responsible and Sustainable Development in the Built Environment for future action and development. It examines the methods of evaluation, the use of technology, the creation of new models and the role of human factors for examining and developing the subject over the next twenty years.

10922.84 рублей

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A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.

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