puneet kumar ankita mehta and rahul deshmukh calcium channel blockers against mptp induced parkinson’s in rats

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Scott Cooper P. Atlas of Natural and Induced Fractures in Core

An invaluable reference that helps geologists recognize and differentiate the many types of natural fractures, induced fractures and artefacts found in cores Atlas of Natural and Induced Fractures in Core offers a reference for the interpretation of natural and induced fractures in cores. The natural and induced fracture data contained in cores provides a wealth of information once they are recognized and properly interpreted. Written by two experts in the field, this resource provides a much-needed tool to help with the accurate interpretation of these cores. The authorsinclude the information needed to identify different fracture types as well as the criteria for distinguishing between the types of fractures. The atlas shows how to recognize non-fracture artefacts in a core since many of them provide other types of useful information. In addition, the text’s illustrated structures combined with their basic interpretations are designed to be primary building blocks of a complete fracture assessment and analysis. The authors show how to recognize and correctly interpret these building blocks to ensure that subsequent analyses, interpretations, and modeling efforts regarding fracture-controlled reservoir permeability are valid. Presented in full color throughout, this comprehensive reference is written for geologists charged with interpreting fracture-controlled permeability systems in reservoirs as well as for students or other scientists who need to develop the skills to accurately interpret the natural and induced fractures in cores.

10872.62 рублей

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Vincent Savaux MMSE-Based Algorithm for Joint Signal Detection, Channel and Noise Variance Estimation for OFDM Systems

This book presents an algorithm for the detection of an orthogonal frequency division multiplexing (OFDM) signal in a cognitive radio context by means of a joint and iterative channel and noise estimation technique. Based on the minimum mean square criterion, it performs an accurate detection of a user in a frequency band, by achieving a quasi-optimal channel and noise variance estimation if the signal is present, and by estimating the noise level in the band if the signal is absent. Organized into three chapters, the first chapter provides the background against which the system model is presented, as well as some basics concerning the channel statistics and the transmission of an OFDM signal over a multipath channel. In Chapter 2, the proposed iterative algorithm for the noise variance and the channel estimation is detailed, and in Chapter 3, an application of the algorithm for the free-band detection is proposed. In both Chapters 2 and 3, the principle of the algorithm is presented in a simple way, and more elaborate developments are also provided. The different assumptions and assertions in the developments and the performance of the proposed method are validated through simulations, and compared to methods of the scientific literature

5291.2 рублей

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Anthony Campbell K. Fundamentals of Intracellular Calcium

The definitive text on the key component for cell functions—intracellular calcium This comprehensive book reveals the evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells. It shows how the components required for calcium signaling are named and classified; covers the technology that has been developed to study intracellular calcium; describes how calcium is regulated inside cells and how it works to trigger an event; explains the role of intracellular calcium in disease, cell injury, and cell death; reveals how many drugs work through the calcium signaling system; and demonstrates how intracellular calcium is involved in the action of many natural toxins. The book also illustrates how the intracellular calcium signaling system has evolved over millions of years, showing why it was crucial to the origin of life. Additionally, the book promotes the importance of the molecular variation upon which the intracellular calcium signalling system depends. Featuring more than 100 figures (including detailed chemical structures as well as pictures of key pioneers in the field), a bibliography of some 1000 references, and a detailed subject index, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond. Emphasizes two key scientific principles—the first to show how intracellular Ca2+ acts as a switch, to activate a wide range of cellular events, and the second demonstrating how an analogue mechanism can be superimposed on such a process Written by an internationally recognized expert in the field Filled with images and references to facilitate learning Fundamentals of Intracellular Calcium is an all-important text for post-graduate students and researchers working in biomedicine and biochemistry. It is also essential for undergraduate lecturers and their students in physiology, medicine, pharmacy, and the biosciences.

6885.99 рублей

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Printio To the rats and wolves

Футболка с полной запечаткой для мальчиков. Обложка немецкой группы с последнего альбома To the Rats and Wolves.

1290 рублей

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Yehuda Shoenfeld Vaccines and Autoimmunity

In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

12319.55 рублей

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Printio To the rats and wolves

Футболка с полной запечаткой (мужская) — пол: МУЖ, материал: СИНТЕТИКА. Обложка немецкой группы с последнего альбома To the Rats and Wolves.

1290 рублей

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Anthony Campbell K. Intracellular Calcium

Thousands of imaginative scientists, over more than a century, have revealed the fascinating story of intracellular calcium, through a pathway of ingenious invention and discovery. Intracellular Calcium, the definitive book on this topic, reveals: The pathway of discovery and invention of intracellular calcium over more than 100 years. The evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells How the components required for calcium signalling are named and classified. The ingenious technology, which has been developed to study intracellular calcium. How calcium is regulated inside cells and how it works to trigger an event. The role of intracellular calcium in disease, cell injury and cell death. How many drugs work through the calcium signalling system. How intracellular calcium is involved in the action of many natural toxins. How the intracellular calcium signalling system has evolved over 4000 million years, showing why it was crucial to the origin of life. A key principle presented throughout the book is the molecular variation upon which the intracellular calcium signalling system depends. This variation occurs within the same cell type and between cells with different functions, providing the invisible matrix upon which Darwin and Wallace’s Natural Selection depends. Featuring more than 100 figures, including detailed chemical structures as well as pictures of key pioneers in the field, a bibliography of more than 1500 references, as well as detailed subject and organism indices, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond.

26234.73 рублей

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Qiuhong Tang Terrestrial Water Cycle and Climate Change. Natural and Human-Induced Impacts

The Terrestrial Water Cycle: Natural and Human-Induced Changes is a comprehensive volume that investigates the changes in the terrestrial water cycle and the natural and anthropogenic factors that cause these changes. This volume brings together recent progress and achievements in large-scale hydrological observations and numerical simulations, specifically in areas such as in situ measurement network, satellite remote sensing and hydrological modeling. Our goal is to extend and deepen our understanding of the changes in the terrestrial water cycle and to shed light on the mechanisms of the changes and their consequences in water resources and human well-being in the context of global change. Volume highlights include: Overview of the changes in the terrestrial water cycle Human alterations of the terrestrial water cycle Recent advances in hydrological measurement and observation Integrated modeling of the terrestrial water cycle The Terrestrial Water Cycle: Natural and Human-Induced Changes will be a valuable resource for students and professionals in the fields of hydrology, water resources, climate change, ecology, geophysics, and geographic sciences. The book will also be attractive to those who have general interests in the terrestrial water cycle, including how and why the cycle changes.

13468.01 рублей

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Printio To the rats and wolves

Футболка с полной запечаткой для девочек. Обложка немецкой группы с последнего альбома To the Rats and Wolves.

1290 рублей

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Anjun Qin Aggregation-Induced Emission. Fundamentals

Aggregation-Induced Emission (AIE) is a novel photophysical phenomenon which offers a new platform for researchers to look into the light-emitting processes from luminogen aggregates, from which useful information on structure–property relationships may be collected and mechanistic insights may be gained. The discovery of the AIE effect opens a new avenue for the development of new luminogen materials in the aggregate or solid state. By enabling light emission in the practically useful solid state, AIE has the potential to expand significantly the technological applications of luminescent materials. Aggregation-Induced Emission: Fundamentals is the first book to explore the fundamental issues of AIE, including the design, synthesis, and photophysical behavior of AIE-active molecules and polymers. The control of the morphological structures of the aggregates of AIE-active materials, and the experimental investigation and theoretical understanding of the AIE mechanism, are also covered in this volume. Topics covered include: AIE in group 14 metalloles AIE in organic ion pairs Red light-emitting AIE materials Supramolecular structure and AIE AIE-active polymers Enhanced emission by restriction of molecular rotation Crystallization-induced emission enhancement Theoretical understanding of AIE phenomena This book is essential reading for scientists and engineers who are designing optoelectronic materials and biomedical sensors, and will also be of interest to academic researchers in materials science and physical and synthetic organic chemistry, as well as physicists and biological chemists.

16091.61 рублей

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Haggard Henry Rider The Lady of Blossholme

This is a tale of adventure and derring-do set in the time of King Henry VIII and the pilgrimage of grace. This was the period when King Henry was rebelling against Pope Clement VII, and when many Englishmen in the north, and many clergymen, were rebelling against Henry, in the so-called Pilgrimage of Grace. To raise needed funds for this rebellion against the king, the Spanish abbot Clement Maldon murders Cicely Foterell's father and tries to claim all the family's lands and jewels.

552 рублей

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Saura Sahu C. microRNAs in Toxicology and Medicine

During the past decade it has become evident that microRNAs regulate gene expressions and control many developmental and cellular processes in eukaryotic organisms. Recent studies suggest that microRNAs play an important role in toxicogenomics and are likely to play an important role in a range of human diseases including cancer. microRNAs in Toxicology and Medicine is a comprehensive and authoritative compilation of up-to-date developments in this emerging research area, presented by internationally recognized investigators. It focuses on the role of microRNA in biology and medicine with a special emphasis on toxicology. Divided into six parts, topics covered include: microRNA and toxicology – including environmental toxicants and perturbation of miRNA signaling; microRNA, and Disease States featuring microRNAs in drug-induced liver toxicity, microRNAs and Inflammation the regulatory role of microRNA in mutagenesis, microRNAs and cancer, and the role of microRNAs in tumor progression and therapy, as well as current understanding of microRNAs as therapeutic targets in cancer microRNAs and disease states microRNAs and stem cells microRNAs and genomics microRNAs and epigenomics microRNAs and biomarkers – including body fluid microRNAs as toxicological biomarkers, cell-free microRNAs as biomarkers in human diseases, and circulating microRNAs as biomarkers of drug-induced pancreatitis microRNAs in Toxicology and Medicine is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors, and regulators in academia, medical settings, industry, and government.

16599.14 рублей

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Etienne Frossard Granular Geomaterials Dissipative Mechanics. Theory and Applications in Civil Engineering

This book develops a new vision in geomechanics which will be of interest to researchers and engineers. It begins with the key theoretical features of dissipative structures induced by elementary contact friction within geomaterials in slow motion, their multi-scale expression in key tensor relations and associated features including strain localization and shear banding.

14351.94 рублей

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The definitive text on the key component for cell functions—intracellular calcium This comprehensive book reveals the evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells. It shows how the components required for calcium signaling are named and classified; covers the technology that has been developed to study intracellular calcium; describes how calcium is regulated inside cells and how it works to trigger an event; explains the role of intracellular calcium in disease, cell injury, and cell death; reveals how many drugs work through the calcium signaling system; and demonstrates how intracellular calcium is involved in the action of many natural toxins. The book also illustrates how the intracellular calcium signaling system has evolved over millions of years, showing why it was crucial to the origin of life. Additionally, the book promotes the importance of the molecular variation upon which the intracellular calcium signalling system depends. Featuring more than 100 figures (including detailed chemical structures as well as pictures of key pioneers in the field), a bibliography of some 1000 references, and a detailed subject index, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond. Emphasizes two key scientific principles—the first to show how intracellular Ca2+ acts as a switch, to activate a wide range of cellular events, and the second demonstrating how an analogue mechanism can be superimposed on such a process Written by an internationally recognized expert in the field Filled with images and references to facilitate learning Fundamentals of Intracellular Calcium is an all-important text for post-graduate students and researchers working in biomedicine and biochemistry. It is also essential for undergraduate lecturers and their students in physiology, medicine, pharmacy, and the biosciences.

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