krishna kaveri das debabrata panda and ramani kumar sarkar screening of submergence tolerance in rice

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Jeannette Milgrom Identifying Perinatal Depression and Anxiety. Evidence-based Practice in Screening, Psychosocial Assessment and Management

Identifying Perinatal Depression and Anxiety brings together the very latest research and clinical practice on this topic from around the world in one valuable resource. Examines current screening and management models, particularly those in Australia, England and Wales, Scotland, and the United States Discusses the evidence, accuracy, and limitations of screening methods in the context of challenges, policy issues, and questions that require further research Up to date practical guidance of how to screen, assess, diagnose and manage is provided. Considers the importance of screening processes that involve infants and fathers, additional training for health professionals, pathways to care following screening, and the economics of screening Offers forward-thinking synthesis and analysis of the current state of the field by leading international experts, with the goal of sketching out areas in need of future research

3744.81 рублей

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Sajal Das Kumar Mobile Terminal Receiver Design. LTE and LTE-Advanced

Combines in one volume the basics of evolving radio access technologies and their implementation in mobile phones Reviews the evolution of radio access technologies (RAT) used in mobile phones and then focuses on the technologies needed to implement the LTE (Long term evolution) capability Coverage includes the architectural aspects of the RF and digital baseband parts before dealing in more detail with some of the hardware implementation Unique coverage of design parameters and operation details for LTE-A phone transceiver Discusses design of multi-RAT Mobile with the consideration of cost and form factors Provides in one book a review of the evolution of radio access technologies and a good overview of LTE and its implementation in a handset Unveils the concepts and research updates of 5G technologies and the internal hardware and software of a 5G phone

11780.78 рублей

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Rosalind Eeles A. Cancer Prevention and Screening. Concepts, Principles and Controversies

Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques

9575.17 рублей

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Mengfei Yang Fault-Tolerance Techniques for Spacecraft Control Computers

Comprehensive coverage of all aspects of space application oriented fault tolerance techniques • Experienced expert author working on fault tolerance for Chinese space program for almost three decades • Initiatively provides a systematic texts for the cutting-edge fault tolerance techniques in spacecraft control computer, with emphasis on practical engineering knowledge • Presents fundamental and advanced theories and technologies in a logical and easy-to-understand manner • Beneficial to readers inside and outside the area of space applications

10497.42 рублей

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Pablo Steinberg High-Throughput Screening Methods in Toxicity Testing

Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's «Toxicity Testing in the 21st Century: A Vision and Strategy» and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing. High-Throughput Screening Methods in Toxicity Testing is divided into five parts: General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling Assessing different cytotoxicity endpoints Assessing DNA damage and carcinogenesis Assessing reproductive toxicity, cardiotoxicity, and haematotoxicity Assessing drug metabolism and receptor-related toxicity Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined. Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods. This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.

12644.28 рублей

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Wood Terry Management of Chemical and Biological Samples for Screening Applications

Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.

15862.82 рублей

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Hugo Kubinyi Virtual Screening. Principles, Challenges, and Practical Guidelines

Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable degree of accuracy. Alternatively, if active ligands are already available, molecular similarity searches can be used to find new molecules. This virtual screening can even be applied to compounds that have yet to be synthesized, as opposed to «real» screening that requires cost- and labor-intensive laboratory testing with previously synthesized drug compounds. Unique in its focus on the end user, this is a real «how to» book that does not presuppose prior experience in virtual screening or a background in computational chemistry. It is both a desktop reference and practical guide to virtual screening applications in drug discovery, offering a comprehensive and up-to-date overview. Clearly divided into four major sections, the first provides a detailed description of the methods required for and applied in virtual screening, while the second discusses the most important challenges in order to improve the impact and success of this technique. The third and fourth, practical parts contain practical guidelines and several case studies covering the most important scenarios for new drug discovery, accompanied by general guidelines for the entire workflow of virtual screening studies. Throughout the text, medicinal chemists from academia, as well as from large and small pharmaceutical companies report on their experience and pass on priceless practical advice on how to make best use of these powerful methods.

16271.14 рублей

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Challa S. S. R. Kumar Microfluidic Devices in Nanotechnology. Fundamental Concepts

Nanotechnology, especially microfabrication, has been affecting every facet of traditional scientific disciplines. The first book on the application of microfluidic reactors in nanotechnology, Microfluidic Devices in Nanotechnology provides the fundamental aspects and potential applications of microfluidic devices, the physics of microfluids, specific methods of chemical synthesis of nanomaterials, and more. As the first book to discuss the unique properties and capabilities of these nanomaterials in the miniaturization of devices, this text serves as a one-stop resource for nanoscientists interested in microdevices.

13027.44 рублей

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Armstrong Natalie The Sociology of Medical Screening. Critical Perspectives, New Directions

The Sociology of Medical Screening: Critical Perspectives, New Directions presents a series of readings that provide an up-to-date overview of the diverse sociological issues relating to population-based medical screening. Features new research data in most of the contributions Includes contributions from eminent sociologists such as David Armstrong, Stefan Timmermans, and Alison Pilnick Represents one of the only collections to specifically address the sociology of medical screening

3058.56 рублей

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Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

11997.76 рублей

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Sally Blythe Goddard Neuromotor Immaturity in Children and Adults. The INPP Screening Test for Clinicians and Health Practitioners

Available to healthcare professionals for the first time, this book contains proven screening tests to measure neuromotor immaturity in children and adults in order to provide a basis for referral and help. Allows practitioners to screen for disorders of movement that can negatively affect educational performance and emotional function in children and adolescents Assesses instances where disorders of movement in adults are affecting thoughts and behavior, as in panic disorder Provides a novel approach for health care professionals observing aberrant reflexes in the absence of more serious pathology Includes reproducible scoring and observation sheets for practice and serves as the perfect complement to Assessing Neuromotor Readiness for Learning

7269.8 рублей

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Rankovic Zoran Lead Generation Approaches in Drug Discovery

An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discovery, including: The evolution of the lead discovery process, key concepts, current challenges, and future directions Strategies and technologies driving the high-throughput screening (HTS) approach to lead discovery, including the shifting paradigms in the design of compound collections and best practice in the hit confirmation process Knowledge-based in silico or «virtual» screening Theory and practice of the fragment-based approach to lead discovery The opportunities and challenges presented by multi-target drug discovery (MTDD) De novo design of lead compounds and new approaches to estimating the synthetic accessibility of de novo–designed molecules The impact of natural products on drug discovery, and potential of natural product–like compounds for exploring regions of biologically relevant chemical space Using early screening of hits and leads for metabolic, pharmacokinetic, and toxicological liabilities to reduce attrition during the later phases of drug discovery The utility of parallel synthesis and purification in lead discovery With each topic supported by numerous case studies, this is indispensable reading for researchers in industry and academia who wish to keep up to date with the latest strategies and approaches in drug discovery.

9349.1 рублей

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Christophe Bouvet Mechanics of Aeronautical Composite Materials

This book presents the principles of composite laminate sizing widely used for composite structures. The focus is on aeronautics in particular, including the concepts of limit loads and ultimate loads. After a brief overview of the main composite materials used in aeronautics, the basic theory of laminated plates and the associated rupture criteria are given. The author presents two fundamental cases of the sizing of aeronautical composite structures: the calculation of the holed structures and their subsequent multi-bolt joints, and the calculation of the buckling. The concept of damage tolerance is also explored, with a focus on its application for tolerance to impact damage. These notions are fundamental for understanding the specificities of the sizing of aeronautical composite structures. The book also contains corrected exercises for the reader to test their understanding of the different topics covered.

9372.7 рублей

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Mayr Lorenz M. Label-Free Technologies For Drug Discovery

Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery. Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis. Label-Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.

13947.02 рублей

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Wenbing Zhao Building Dependable Distributed Systems

This book covers the most essential techniques for designing and building dependable distributed systems. Instead of covering a broad range of research works for each dependability strategy, the book focuses only a selected few (usually the most seminal works, the most practical approaches, or the first publication of each approach) are included and explained in depth, usually with a comprehensive set of examples. The goal is to dissect each technique thoroughly so that readers who are not familiar with dependable distributed computing can actually grasp the technique after studying the book. The book contains eight chapters. The first chapter introduces the basic concepts and terminologies of dependable distributed computing, and also provide an overview of the primary means for achieving dependability. The second chapter describes in detail the checkpointing and logging mechanisms, which are the most commonly used means to achieve limited degree of fault tolerance. Such mechanisms also serve as the foundation for more sophisticated dependability solutions. Chapter three covers the works on recovery-oriented computing, which focus on the practical techniques that reduce the fault detection and recovery times for Internet-based applications. Chapter four outlines the replication techniques for data and service fault tolerance. This chapter also pays particular attention to optimistic replication and the CAP theorem. Chapter five explains a few seminal works on group communication systems. Chapter six introduces the distributed consensus problem and covers a number of Paxos family algorithms in depth. Chapter seven introduces the Byzantine generals problem and its latest solutions, including the seminal Practical Byzantine Fault Tolerance (PBFT) algorithm and a number of its derivatives. The final chapter covers the latest research results on application-aware Byzantine fault tolerance, which is an important step forward towards practical use of Byzantine fault tolerance techniques.

14330.18 рублей

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Updesh Kumar The Wiley Handbook of Personality Assessment

The Wiley Handbook of Personality Assessment presents the state-of-the-art in the field of personality assessment, providing a perspective on emerging trends, and placing these in the context of research advances in the associated fields. Explores emerging trends and perspectives in personality assessment, building on current knowledge and looking ahead to the future landscape of the field Discusses emerging technologies and how these can be combined with psychological theories in order to enhance the real-world practice of assessing personality Comprehensive sections address gaps in current knowledge and collate contributions and advances from diverse areas and perspectives The chapter authors are eminent scholars from across the globe who bring together new research from many different countries and cultures

14622.12 рублей

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Narendra Tuteja Improving Crop Productivity in Sustainable Agriculture

An up-to-date overview of current progress in improving crop quality and quantity using modern methods. With a particular emphasis on genetic engineering, this text focusses on crop improvement under adverse conditions, paying special attention to such staple crops as rice, maize, and pulses. It includes an excellent mix of specific examples, such as the creation of nutritionally-fortified rice and a discussion of the political and economic implications of genetically engineered food. The result is a must-have hands-on guide, ideally suited for the biotech and agro industries.

16492.39 рублей

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Sabu Thomas Advanced Materials for Electromagnetic Shielding. Fundamentals, Properties, and Applications

A comprehensive review of the field of materials that shield people and sensitive electronic devices from electromagnetic fields Advanced Materials for Electromagnetic Shielding offers a thorough review of the most recent advances in the processing and characterization of the electromagnetic shielding materials. In this groundbreaking book, the authors—noted experts in the field—discuss the fundamentals of shielding theory as well as the practice of electromagnetic field measuring techniques and systems. They also explore applications of shielding materials used as absorbers of electromagnetic radiation, or as magnetic shields and explore coverage of new advanced materials for EMI shielding in aerospace applications. In addition, the text contains methods of preparation and applicability of metal foams. This comprehensive text examines the influence of technology on the micro-and macrostructure of polymers enabling their use in screening technology, technologies of shielding materials based on textiles, and analyses of its effectiveness in screening. The book also details the method of producing nanowires and their applications in EM shielding. This important resource: Explores the burgeoning market of electromagnetic shielding materials as we create, depend upon, and are exposed to more electronic devices than ever Addresses the most comprehensive issues relating to electromagnetic fields Contains information on the manufacturing, characterization methods, and properties of materials used to protect against them Discusses the important characterization techniques compared with one another, thus allowing scientists to select the best approach to a problem Written for materials scientists, electrical and electronics engineers, physicists, and industrial researchers, Advanced Materials for Electromagnetic Shielding explores all aspects in the area of electromagnetic shielding materials and examines the current state-of-the-art and new challenges in this rapidly growing area.

20690.64 рублей

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Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

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