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This compilation of proceedings covering the latest scientific and technological developments in design, development, and applications of engineering ceramics and composites provides a useful one-stop resource for understanding the most important issues in design, development, and applications of engineering ceramics and composites. Logically organized and carefully selected articles give insight into design, development, and applications of engineering ceramics and composites and incorporates the latest developments related to design, development, and applications of engineering ceramics and composites including developments in engineering ceramics, advanced ceramic coatings, and geopolymers.
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Provides a clear, useful framework and methods for R&D, including robust technology development, product planning, and product design and development management Quality Strategy for Research and Development integrates the Japanese and Western perspectives on Quality Function Deployment (QFD), updates the strategy of Robust Engineering (RE), and relates their unique frameworks to current, widely adopted philosophies of quality assurance. Featuring real-world case studies, more than thirty tables, and over seventy figures, this essential guide identifies key issues and proposes improvements in the current R&D paradigm. It offers in-depth coverage of technology development, product planning, and product design and development management. Quality Strategy for Research and Development: Updates the conventional approaches to QFD and RE, and provides the implementation model of combining them into a corporate operating system Identifies key issues in the current practice of R&D, and provides solutions for improving design quality and R&D productivity Includes the case studies of designing a functional circuit, magnetic component, measurement system, and machining equipment Offers the integration models of QFD and other breakthrough strategies including DFX (Design For eXcellence), DFSS (Design For Six Sigma), and Blue Ocean Strategy Written for R&D executives, managers, engineers, and quality practitioners, Quality Strategy for Research and Development is also an ideal text for professors and students of industrial and systems engineering, technology management, and business administration.
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The evolution of sustainability, with a practical framework for integration Regenerative Development and Design takes sustainability to the next level, and provides a framework for incorporating regenerative design principles into your current process. The Regenesis Group is a coalition of experienced design, land-use, planning, business, and development professionals who represent the forefront of the movement; in this book, they explain what regenerative development is, how and why it works, and how you can incorporate the fundamental principles into your practice. A clear, focused framework shows you how to merge regenerative concepts with your existing work, backed by numerous examples that guide practical application while illustrating regenerative design and development in action. As the most comprehensive and systemic approach to regenerative development, this book is a must-have resource for architects, planners, and designers seeking the next step in sustainability. Regenerative design and development positions humans as co-creative and mutually-evolving participants in an ecosystem—not just a built environment. This book describes how to bring that focus to your design from the earliest stages. Understand the fundamentals of regenerative design and development Learn how regenerative development contributes to sustainability Integrate regenerative development concepts into practice Examine sample designs that embody the regenerative concept To create a design with true sustainability, considerations must extend far beyond siting, materials, and efficiency. Designers must look at the place, it's inhabitants, and the purpose—the whole living ecosystem—and proceed with their work from that more humbling perspective. The finished product should itself be an ecosystem and sustainable economy, which is the root of the regenerative development approach. Sustainability has evolved, and the designer's responsibility has increased in kind. Regenerative Development and Design provides an authoritative resource for those ready to take the next step forward.
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The use of computers has opened up remarkable opportunities for innovative design, improved productivity, and greater efficiency in the use of materials. Uniquely, this book focuses on the practical use of computers for clothing pattern design and product development. Readers are introduced to the various computer systems which are suitable for the industry, the principles and techniques of pattern design applied to computer systems are explained, and readers are shown how product data management can be used in clothing product development.
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This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code
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…Extraordinary: Gibbs has popped the hood and taken apart the engine of commercial design and development, showing us each individual part and explaining fit, form and function. —Yaromir Steiner, Founder, Chief Executive Officer, Steiner + Associates «…the most comprehensive and expansive book ever written on the subject of Retail Real Estate Development. Gibbs is by far the most prominent advocate for reforming retail planning and development in order to return American cities to economic and physical prominence.» –Stefanos Polyzoides, Moule & Polyzoides Architects & Urbanists The retail environment has evolved rapidly in the past few decades, with the retailing industry and its placement and design of «brick-and-mortar» locations changing with evolving demographics, shopping behavior, transportation options and a desire in recent years for more unique shopping environments. Written by a leading expert, this is a guide to planning for retail development for urban planners, urban designers and architects. It includes an overview of history of retail design, a look at retail and merchandising trends, and principles for current retail developments. Principles of Urban Retail Planning and Development will: Provide insight and techniques necessary for historic downtowns and new urban communities to compete with modern suburban shopping centers. Promote sustainable community building and development by making it more profitable for the shopping center industry to invest in historic cities or to develop walkable urban communities. Includes case studies of recent good examples of retail development
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A thorough treatment of product and systems development in terms of value to all stakeholders Product and Systems Development compiles more than twenty years of research and practice from a value perspective, from vision and marketing to design, manufacturing, delivery, operations, and maintenance. It defines stakeholder value and identifies specific stakeholders in the product and system development process; covers best practices in development; and examines systems engineering, current industry views, and the life cycle of a value stream. Featuring appendices written by professionals in the field on topics such as Design Structure Matrices, Lean Enablers for systems engineering, and MDAO and simulations, this indispensable guide: Explains why stakeholders' values can hold the key to fulfillment or defeat of the developer's vision Emphasizes the succession of value-contributing practices and tools that form a framework for development success Integrates the technical, productivity, and customer/end-user elements in product and system development Uses more than 100 tables and figures to illustrate the above processes, as well as corollary elements of risk, failure analysis, and fault-tolerant design Includes numerous case studies and links to online material Product and Systems Development is an excellent coursebook for senior and graduate students in aerospace, mechanical, civil, electrical, and material engineering, as well as management science and engineering. It is also a useful reference for practicing engineers in a variety of technology-based industries.
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Christine Seymour Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture
Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities. Highlights Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications Chapters are devoted to applications of QbD methodology in three main processing sectors—drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process.
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RF and Microwave Transmitter Design is unique in its coverage of both historical transmitter design and cutting edge technologies. This text explores the results of well-known and new theoretical analyses, while informing readers of modern radio transmitters' pracitcal designs and their components. Jam-packed with information, this book broadcasts and streamlines the author's considerable experience in RF and microwave design and development.
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Develop a more systematic, human-centered, results-oriented thought process Design Thinking is the Product Development and Management Association's (PDMA) guide to better problem solving and decision-making in product development and beyond. The second in the New Product Development Essentials series, this book shows you how to bridge the gap between the strategic importance of design and the tactical approach of design thinking. You'll learn how to approach new product development from a fresh perspective, with a focus on systematic, targeted thinking that results in a repeatable, human-centered problem-solving process. Integrating high-level discussion with practical, actionable strategy, this book helps you re-tool your thought processes in a way that translates well beyond product development, giving you a new way to approach business strategy and more. Design is a process of systematic creativity that yields the most appropriate solution to a properly identified problem. Design thinking disrupts stalemates and brings logic to the forefront of the conversation. This book shows you how to adopt these techniques and train your brain to see the answer to any question, at any level, in any stage of the development process. Become a better problem-solver in every aspect of business Connect strategy with practice in the context of product development Systematically map out your new product, service, or business Experiment with new thought processes and decision making strategies You can't rely on old ways of thinking to produce the newest, most cutting-edge solutions. Product development is the bedrock of business —whether your «product» is a tangible object, a service, or the business itself – and your approach must be consistently and reliably productive. Design Thinking helps you internalize this essential process so you can bring value to innovation and merge strategy with reality.
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Now covering both conventional and unmanned systems, this is a significant update of the definitive book on aircraft system design Design and Development of Aircraft Systems, Second Edition is for people who want to understand how industry develops the customer requirement into a fully integrated, tested, and qualified product that is safe to fly and fit for purpose. This edition has been updated to take into account the growth of unmanned air vehicles, together with updates to all chapters to bring them in line with current design practice and technologies as taught on courses at BAE Systems and Cranfield, Bristol and Loughborough universities in the UK. Design and Development of Aircraft Systems, Second Edition Provides a holistic view of aircraft system design describing the interaction between all of the subsystems such as fuel system, navigation, flight control etc. Covers all aspects of design including systems engineering, design drivers, systems architectures, systems integration, modelling of systems, practical considerations, & systems examples. Incorporates essential new material on Unmanned Aircraft Systems (UAS). Design and Development of Aircraft Systems, Second Edition has been written to be generic and not to describe any single process. It aims to complement other volumes in the Wiley Aerospace Series, in particular Aircraft Systems, Third Edition and Civil Avionics Systems by the same authors, and will inform readers of the work that is carried out by engineers in the aerospace industry to produce innovative and challenging – yet safe and reliable – systems and aircraft. Essential reading for Aerospace Engineers.
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Written primarily for directors and managers of food design and development, food scientists, technologists, and product developers, this book explains all the necessary information in order to help meet the increasing demands for innovation in an industry that is providing fewer resources. This updated edition, by a group of seasoned food industry business professionals and academics, provides a real-world perspective of what is occurring in the food industry right now, offers strategic frameworks for problem solving and R&D strategies, and presents methods needed to accelerate and optimize new product development. Accelerating New Food Product Design and Development, Second Edition features five brand new chapters covering all the changes that have occurred within the last decade: A Flavor Supplier Perspective, An Ingredient Supplier Perspective, Applying Processes that Accelerate New Product Development, Looking at How the University Prepares Someone for a Career in Food, and Innovative Packaging and Its Impact on Accelerated Product Development. Offers new perspectives on what really goes on during the development process Includes updated chapters fully describing the changes that have occurred in the food industry, both from a developer’s point of view as well as the consumer requirements Features a completely rewritten chapter covering the importance of packaging which is enhanced through 3D printing All of this against the impact on speed to market Filled with unique viewpoints of the business from those who really know and a plethora of new information, Accelerating New Food Product Design and Development, Second Edition will be of great interest to all professionals engaged in new food product design and development.
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Sara A. Hurvitz Antibody-Drug Conjugates. Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer
Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development
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