ayad hameed khulood al samerai and alaa al–haddad synthesis and bioligical evaluation of some new 1 3 4 oxadiazole

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Humphrey Davies Friendly Fire

The new book from Alaa Al Aswany, author of the international bestsellers The Yacoubian Building and ChicagoFriendly Fire is a novella and collection of short stories from Alaa Al Aswany, author of the bestselling The Yacoubian Building. As in that novel, Al Aswany dissects modern Egyptian society and reveals with skill and detachment the hypocrisy, violence and abuse of power characteristic of a world in moral crisis. Here, though, the focus has shifted from the broad historical canvas to the minute stitches of pain that hold together an individual, a family, a school classroom, or the relationship between a man and a woman. Can a man so alienated from his society that he regards all its members as no better than microbes wriggling under a microscope survive within it? Can cynical religiosity triumph over human decency? Can a man put the thought of a delicious dish of beans behind him long enough to mourn his father's death? Alongside these wry questions, other, less mordant perspectives also have their place: an ageing cabaret dancer bestows the blessing of a vanished world on her lover's son; a crippled boy wins subjective victory from objective disaster. In Friendly Fire, readers will find again the vivid, passionate characters of today's Cairo, clamouring to be heard.Friendly Fire also features an introduction by Alaa Al Aswany giving the history of the novella, 'The Isam Abd el-Ati Papers', which was banned in Egypt for a decade.

712.82 рублей

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Johnson Douglas S. Modern Drug Synthesis

Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of twenty different drug molecules.

10192.06 рублей

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David Williams D. Seven North American Evaluation Pioneers. New Directions for Evaluation, Number 150

How do people evaluate in daily life? This issue broaches this topic to better understand this dimension of being human, to develop evaluation theory, and to improve extraprofessional and professional evaluation practice. As part of a larger study addressing these issues in the lives of many professional evaluators around the world, case studies of seven early evaluation theorists and practitioners from North America were conducted. This issue contains articles with stories of some of their evaluation life experiences told and interpreted by these individuals, with commentary by an eighth evaluator. Themes that cross the cases are proposed, and responses by the individuals highlighted are shared in a final article. This is the 150th issue in the New Directions for Evaluation series from Jossey-Bass. It is an official publication of the American Evaluation Association.

2174.04 рублей

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Sandra Mathison Really New Directions in Evaluation: Young Evaluators' Perspectives. New Directions for Evaluation, Number 131

This issue of New Directions for Evaluation (NDE) marks a milestone: the 25th anniversary of the American Evaluation Association (AEA). NDE is an official publication of AEA and has been a crucial means for the Association to foster and promote the professionalization of evaluation through thematic discussions of theory and practice in evaluation. NDE was first published in 1978 under the name New Directions for Program Evaluation, although the title became New Directions for Evaluation in 1995 in acknowledgement of the broader scope of evaluation.

2220.23 рублей

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Lockwood Craig Synthesizing Qualitative Research. Choosing the Right Approach

A considerable number of journal publications using a range of qualitative synthesis approaches has been published. Mary Dixon-Woods and colleagues (Mary Dixon-Woods, Booth, & Sutton, 2007) identified 42 qualitative evidence synthesis papers published in health care literature between 1990 and 2004. An ongoing update by Hannes and Macaitis (2010)identified around 100 additional qualitative or mixed methods syntheses. Yet these generally lack a clear, detailed description of what was done and why (Greenhalgh et al, 2007; McInnes & Wimpenny, 2008). Choices are most commonly influenced by what others have successfully used in the past or by a particular school of thought (Atkins et al, 2008; Britten et al, 2002). This is a substantive limitation. This book brings balance to the options available to researchers, including approaches that have not had a substantial uptake among researchers. It provides arguments for when and why researchers or other parties of interest should opt for a certain approach to synthesis, which challenges they might face in adopting it and what the potential strengths and weaknesses are compared with other approaches. This book acts as a resource for readers who would otherwise have to piece together the methodology from a range of journal articles. In addition, it should stimulate further development and documentation of synthesis methodology in a field that is characterized by diversity.

4900.62 рублей

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Sandra Mathison Really New Directions in Evaluation: Young Evaluators' Perspectives. New Directions for Evaluation, Number 131

This issue of New Directions for Evaluation (NDE) marks a milestone: the 25th anniversary of the American Evaluation Association (AEA). NDE is an official publication of AEA and has been a crucial means for the Association to foster and promote the professionalization of evaluation through thematic discussions of theory and practice in evaluation. NDE was first published in 1978 under the name New Directions for Program Evaluation, although the title became New Directions for Evaluation in 1995 in acknowledgement of the broader scope of evaluation.

2174.04 рублей

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Nielsen Steffen Bohni Performance Management and Evaluation. New Directions for Evaluation, Number 137

This issue focuses on connections between performance management and evaluation, a contentious topic at the moment. It does so by placing evaluation and monitoring under the overarching concept of performance management, and then by investigating five complementarities between performance monitoring and measurement on the one hand, and evaluation on the other. These complementarities are: Sequential Informational Organizational Methodical Hierarchical. Several case studies discuss the uses and complementarities of evaluation and performance management in contexts including national and local governments and the work of government, philanthropic foundations, and a direct-service nonprofit agency. These cases illustrate the advantages and pitfalls in utilizing evaluative approaches within the context of performance management. This is the 137th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.

2220.23 рублей

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Dean Spaulding T. Program Evaluation in Practice. Core Concepts and Examples for Discussion and Analysis

An updated guide to the core concepts of program evaluation This updated edition of Program Evaluation in Practice covers the core concepts of program evaluation and uses case studies to touch on real-world issues that arise when conducting an evaluation project. This important resource is filled with illustrative examples written in accessible terms and provides a wide variety of evaluation projects that can be used for discussion, analysis, and reflection. The book addresses foundations and theories of evaluation, tools and methods for collecting data, writing of reports, and the sharing of findings. The discussion questions and class activities at the end of each chapter are designed to help process the information in that chapter and to integrate the information from the other chapters, thus facilitating the learning process. As useful for students as it is for evaluators in training, Program Evaluation in Practice is a must-have text for those aspiring to be effective evaluators. Includes expanded discussion of basic theories and approaches to program evaluation Features a new chapter on objective-based evaluation and a new section on ethics in program evaluation Provides more detailed information and in-depth description for each case, including evaluation approaches, fresh references, new readings, and the new Joint Committee Standards for Evaluation

4981.08 рублей

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Sharlene Hesse-Biber Mixed Methods and Credibility of Evidence in Evaluation. New Directions for Evaluation, Number 138

Mixed methods in evaluation have the potential to enhance the credibility of evaluation and the outcomes of evaluation. This issue explores advances in understanding mixed methods in philosophical, theoretical, and methodological terms and presents specific illustrations of the application of these concepts in evaluation practice. Leading thinkers in the mixed methods evaluation community provide frameworks and strategies that are associated with improving the probability of reaching the goals of enhanced credibility for evaluations, the evidence they produce, and the actions taken as a result of the evaluation findings. This is the 138th volume of the Jossey-Bass quarterly report series New Directions for Evaluation, an official publication of the American Evaluation Association.

2174.04 рублей

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шланг Al-ko 50м 3/4"" 8бар

Al-ko
Длина: 50 м
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3190 рублей

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шланг Al-ko 25м 3/4"" 8бар

Al-ko
Длина: 25 м
Диаметр: 3/4""
Макс. давление: 8 бар

1590 рублей

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Gongkang Fu Bridge Design and Evaluation. LRFD and LRFR

A succinct, real-world approach to complete bridge system design and evaluation Load and Resistance Factor Design (LRFD) and Load and Resistance Factor Rating (LRFR) are design and evaluation methods that have replaced or offered alternatives to other traditional methods as the new standards for designing and load-rating U.S. highway bridges. Bridge Design and Evaluation covers complete bridge systems (substructure and superstructure) in one succinct, manageable package. It presents real-world bridge examples demonstrating both their design and evaluation using LRFD and LRFR. Designed for a 3- to 4-credit undergraduate or graduate-level course, it presents the fundamentals of the topic without expanding needlessly into advanced or specialized topics. Important features include: Exclusive focus on LRFD and LRFR Hundreds of photographs and figures of real bridges to connect the theoretical with the practical Design and evaluation examples from real bridges including actual bridge plans and drawings and design methodologies Numerous exercise problems Specific design for a 3- to 4-credit course at the undergraduate or graduate level The only bridge engineering textbook to cover the important topics of bridge evaluation and rating Bridge Design and Evaluation is the most up-to-date and inclusive introduction available for students in civil engineering specializing in structural and transportation engineering.

10728.48 рублей

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Andrea Trabocchi Diversity-Oriented Synthesis. Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

11997.76 рублей

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Erick Vandamme J. Industrial Biotechnology of Vitamins, Biopigments, and Antioxidants

Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.

18371.19 рублей

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John Tebby C. Alkynes in Cycloadditions

Acetylene systems present a new route to cyclic compounds as an alternative to more traditional methods employed in classical organic chemistry. The synthesis of cyclic structures based on acetylene systems has important applications in the formation of nanostructures, naturally occurring compounds and chemosensory materials for the design of nonlinear optics, electronic and photonic devices. Alkynes in Cycloadditions presents a modern review of regioselective synthesis of aromatic and non-aromatic carbocyclic and heterocyclic ring systems based primarily on [2+2+2] and [4+2] cycloadditions, and other reactions of acetylenic units including enediynes and enyne-allenes. Topics covered include: New strategies for the formation of aromatic and polynuclear hydrocarbons based on (Z)-hex-3-en-1,5-diyne and (Z)-hepta-1,2,4-triene-6-yne blocks. One-step synthesis of benzene derivatives, β-substituted naphthalenes and acenes by the cycloaromatization of enediynes and enyne-allenes by Bergman, Myers-Saito and Shmittel. Mechanisms of cycloaromatization resulting in the formation of fulvene and indene systems. Heterocyclization involving enyne-carbodiimides. New achievements in classical cycloaddition reactions such as the Diels-Alder condensation with acetylenic dienophiles and [2+2] cycloadditions with acetylene components Alkynes in Cycloadditions presents a comprehensive summary of the literature on methods for the synthesis of ring systems from acetylenes for academic researchers working in the fields of organic synthesis, physical organic chemistry, organometallic chemistry, catalysis, materials science, nanomaterials and biochemistry.

14696.81 рублей

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Dutwin Phyllis The ABCs of Evaluation. Timeless Techniques for Program and Project Managers

Thoroughly revised and updated, the third edition of bestselling The ABCs of Evaluation offers an introduction to program evaluation. This comprehensive textbook covers topics such as stakeholder relationships, program design, data collection and analysis, reporting results, and other important steps in the evaluation process. The ABCs of Evaluation shows how to select participants for the evaluation and how to deal with multiple goals and objectives—including those of the organization, the staff, and the client. The authors illustrate the circumstances under which each evaluation model can be used, and offer tips on identifying data sources and collecting the data. This revision includes substantially increased coverage of theory, methodological approaches, the business of evaluation, the evaluator's role and responsibilities, RFPs and the grants process, logic models, data analysis, and writing the evaluation report. Also included are new cases and scenarios from various evaluation realms in social sciences, education, health, and human services. Throughout the book, charts, graphs, models, and lists help organize, extend, and facilitate the understanding of each evaluation concept. Praise for the Previous Edition of The ABCs of Evaluation «A useful general overview of the evaluation process. I would recommend it to program or project managers wanting to know more about the process of evaluation.» —American Journal of Evaluation «All students (and practitioners) should have this in their library; they will use it frequently.» —Patricia McGee, PhD, associate professor, University of Texas, San Antonio Companion Web site: www.josseybass.com/go/Boulmetis

5364.24 рублей

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Stufflebeam Daniel L. Evaluation Theory, Models, and Applications

The golden standard evaluation reference text Now in its second edition, Evaluation Theory, Models, and Applications is the vital text on evaluation models, perfect for classroom use as a textbook, and as a professional evaluation reference. The book begins with an overview of the evaluation field and program evaluation standards, and proceeds to cover the most widely used evaluation approaches. With new evaluation designs and the inclusion of the latest literature from the field, this Second Edition is an essential update for professionals and students who want to stay current. Understanding and choosing evaluation approaches is critical to many professions, and Evaluation Theory, Models, and Applications, Second Edition is the benchmark evaluation guide. Authors Daniel L. Stufflebeam and Chris L. S. Coryn, widely considered experts in the evaluation field, introduce and describe 23 program evaluation approaches, including, new to this edition, transformative evaluation, participatory evaluation, consumer feedback, and meta-analysis. Evaluation Theory, Models, and Applications, Second Edition facilitates the process of planning, conducting, and assessing program evaluations. The highlighted evaluation approaches include: Experimental and quasi-experimental design evaluations Daniel L. Stufflebeam's CIPP Model Michael Scriven's Consumer-Oriented Evaluation Michael Patton's Utilization-Focused Evaluation Robert Stake's Responsive/Stakeholder-Centered Evaluation Case Study Evaluation Key readings listed at the end of each chapter direct readers to the most important references for each topic. Learning objectives, review questions, student exercises, and instructor support materials complete the collection of tools. Choosing from evaluation approaches can be an overwhelming process, but Evaluation Theory, Models, and Applications, Second Edition updates the core evaluation concepts with the latest research, making this complex field accessible in just one book.

6896.88 рублей

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Barbara Rosenstein Evaluation and Social Justice in Complex Sociopolitical Contexts. New Directions for Evaluation, Number 146

This volume is devoted to the theme of social responsibility, social justice, and evaluation. It examines the evaluation–social justice interface and: shares a variety of options and examples from different settings, gives voice to populations whose voices are rarely heard, and contributes to fulfilling the potential of the significant role evaluation can have in promoting social change. First discussing issues related to evaluation, social responsibility, social justice, and marginalized populations in general, it goes on to address issues concerning populations marginalized due to health, psychological, and physical difficulties; their cultural or ethnic/national status; or the specific geopolitical context of Israel. This is the 146th issue in the New Directions for Evaluation series from Jossey-Bass. It is an official publication of the American Evaluation Association.

2174.04 рублей

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Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

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